Histone Deacetylase 11

Known as: EC 3.5.1.98, HD11, HDAC11 
Histone deacetylase 11 (347 aa, ~39 kDa) is encoded by the human HDAC11 gene. This protein is involved in both histone deacetylation and… (More)
National Institutes of Health

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Highly Cited
2010
Highly Cited
2010
PURPOSE Combined-modality treatment consisting of four to six cycles of chemotherapy followed by involved-field radiotherapy… (More)
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Highly Cited
2009
Highly Cited
2009
Antigen-presenting cells (APCs) induce T cell activation as well as T cell tolerance. The molecular basis of the regulation of… (More)
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Highly Cited
2009
Highly Cited
2009
Silencing of the integrated human immunodeficiency virus type 1 (HIV-1) genome in resting CD4(+) T cells is a significant… (More)
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Highly Cited
2009
Highly Cited
2009
Similar to mammalian species, chickens show marked immunological responses to CpG oligodeoxynucleotides (ODNs) both in vivo and… (More)
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2008
2008
Recent studies indicate that neural cell development in the central nervous system (CNS) correlates with a reduction in… (More)
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Highly Cited
2008
Highly Cited
2008
Nonselective inhibitors of human histone deacetylases (HDAC) are known to have antitumor activity in mice in vivo, and several of… (More)
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Highly Cited
2005
Highly Cited
2005
Histone deacetylase inhibitors (HDIs) are a new class of drugs with significant antileukemic activity. To explore mechanisms of… (More)
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2005
2005
Histone deacetylases (HDACs) play a central role in the modification of chromatin structure and thus in the regulation of… (More)
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Highly Cited
2005
Highly Cited
2005
Based upon the recognition of antiviral compounds and single stranded viral RNA the Toll-like receptors TLR7 and TLR8 are… (More)
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Highly Cited
2002
Highly Cited
2002
We have cloned and characterized a human cDNA that belongs to the histone deacetylase family, which we designate as HDAC11. The… (More)
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