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MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression that act by direct base pairing to target… Expand The hippocampus shrinks in late adulthood, leading to impaired memory and increased risk for dementia. Hippocampal and medial… Expand The medial temporal lobe includes a system of anatomically related structures that are essential for declarative memory… Expand Brain-derived neurotrophic factor (BDNF) modulates hippocampal plasticity and hippocampal-dependent memory in cell models and in… Expand Synaptic transmission is a dynamic process. Postsynaptic responses wax and wane as presynaptic activity evolves. This prominent… Expand Theta oscillations represent the "on-line" state of the hippocampus. The extracellular currents underlying theta waves are… Expand In cultures of dissociated rat hippocampal neurons, persistent potentiation and depression of glutamatergic synapses were induced… Expand Medial temporal brain regions such as the hippocampal formation and parahippocampal cortex have been generally implicated in… Expand Ionized calcium (Ca 2÷) is the most common signal transduction element in cells ranging from bacteria to specialized neurons… Expand Recent work has shown that the hippocampus contains a class of receptors for the excitatory amino acid glutamate that are… Expand