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- Toxicologic pathology
The nephrotoxicity of hexachlorobutadiene has been investigated in germ-free rats and compared to conventional rats that have a… (More)
1. The first step in the bioactivation of the nephrotoxin hexachlorobutadiene is the biosynthesis of 1-(glutathion-S-yl)-1,2,3,4… (More)
- Drug metabolism and drug interactions
S-(Pentachlorobutadienyl)-L-cysteine (PCBC) is the penultimate metabolite formed from the nephrocarcinogen hexachlorobutadiene… (More)
- Chemico-biological interactions
The cysteine conjugates of the nephrotoxins hexachlorobutadiene (HCBD), tetrafluoroethylene (TFE) and hexafluoropropene (HFP… (More)