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Hereditary nonpolyposis colorectal carcinoma

National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
BACKGROUND & AIMS The role of the mismatch repair gene PMS2 in hereditary nonpolyposis colorectal carcinoma (HNPCC) is not fully… 
Highly Cited
2006
Highly Cited
2006
Endometrial carcinoma is a common malignancy in hereditary nonpolyposis colorectal carcinoma (HNPCC). Like colon carcinoma… 
Highly Cited
2004
Highly Cited
2004
BACKGROUND & AIMS Hereditary nonpolyposis colorectal carcinoma (HNPCC) is caused by a mutated mismatch repair (MMR) gene. The aim… 
Highly Cited
2004
Highly Cited
2004
Purpose: Immunohistochemistry (IHC) and microsatellite instability (MSI) analysis can be used to identify patients with a… 
Highly Cited
2001
Highly Cited
2001
Cells with deficient DNA mismatch repair develop microsatellite instability. Extensive microsatellite instability (MSI‐high) is… 
Highly Cited
1999
Highly Cited
1999
Hereditary nonpolyposis colorectal carcinoma (HNPCC) is due primarily to inherited mutations in two mismatch repair genes, MSH2… 
Highly Cited
1998
Highly Cited
1998
Patients with hereditary nonpolyposis colorectal carcinoma (HNPCC) reportedly have better prognoses than sporadic colorectal… 
Highly Cited
1998
Highly Cited
1998
Microsatellite instability (MSI) has been detected in endometrial carcinomas occurring in women affected by hereditary… 
Highly Cited
1998
Highly Cited
1998
It has been estimated that the prevalence of carriers of a mutated mismatch repair (MMR) gene among the general population in… 
Highly Cited
1996
Highly Cited
1996
The hereditary nonpolyposis colorectal carcinoma (HNPCC) syndrome is an autosomal dominant genetic disorder caused by the…