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Hereditary Sensory Autonomic Neuropathy, Type 5

Known as: INSENSITIVITY TO PAIN, CONGENITAL, HSAN 5, HSAN Type V 
 
National Institutes of Health

Related topics

Related topics

6 relations
Autosomal recessive inheritanceCongenital Pain InsensitivityHSAN Type IVHereditary Sensory Autonomic Neuropathy, Type 1
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Broader (1)

Hereditary Sensory and Autonomic Neuropathies

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
The NGFR100W Mutation Specifically Impairs Nociception without Affecting Cognitive Performance in a Mouse Model of Hereditary Sensory and Autonomic Neuropathy Type V
Nerve growth factor (NGF) is a key mediator of nociception, acting during the development and differentiation of dorsal root… Expand
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2019
2019
Cholinergic striatal neurons are increased in HSAN V homozygous mice despite reduced NGF bioavailability.
The neurotrophin Nerve growth factor (NGF) plays a critical role in the mature and developing nervous system. A point mutation… Expand
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Review
2019
Review
2019
Painless Nerve Growth Factor: A TrkA biased agonist mediating a broad neuroprotection via its actions on microglia cells
&NA; Nerve Growth Factor (NGF) is a therapeutic candidate for Alzheimer's disease, based on its well known actions on basal… Expand
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2018
2018
Swedish Nerve Growth Factor Mutation (NGFR100W) Defines a Role for TrkA and p75NTR in Nociception
Nerve growth factor (NGF) exerts multiple functions on target neurons throughout development. The recent discovery of a point… Expand
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2018
2018
A third HSAN5 mutation disrupts the nerve growth factor furin cleavage site
Bi-allelic dysfunctional mutations in nerve growth factor (NGF) cause the rare human phenotype hereditary sensory and autonomic… Expand
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Review
2015
Review
2015
Molecular pathogenesis, experimental therapy and genetic counseling in hereditary sensory neuropathies.
Hereditary sensory and autonomic neuropathies (HSANs) represent a group of heritable peripheral nerve disorders usually taking a… Expand
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Review
2014
Review
2014
From genes to pain: nerve growth factor and hereditary sensory and autonomic neuropathy type V.
  • Simona Capsoni
  • The European journal of neuroscience
  • 2014
    • Corpus ID: 205103295
Hereditary sensory and autonomic neuropathy type V (HSAN V) is an autosomal recessive disorder characterized by the loss of deep… Expand
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Review
2011
Review
2011
Pain, pain genetics, and 'next-generation' pain genetics.
Children who suffer pain are frequently seen in clinical practice and unsurprisingly, analgesics are amongst the most common… Expand
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Highly Cited
2010
Highly Cited
2010
A novel NGF mutation clarifies the molecular mechanism and extends the phenotypic spectrum of the HSAN5 neuropathy
Background Nerve growth factor β (NGFβ) and tyrosine kinase receptor type A (TRKA) are a well studied neurotrophin/receptor duo… Expand
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2008
2008
Hereditary sensory and autonomic neuropathy type IV.
Peripheral neuropathy is caused by impaired function of nerve cells called sensory neurons, which transmit information about… Expand
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