Hereditary Melanoma

Known as: Hereditary Cutaneous Melanoma, Melanoma, Familial, Familial Cutaneous Melanoma 
A melanoma defined by the presence of multiple cases of cutaneous melanoma among blood-relatives on the same side of the family. It is caused by… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
GenoMEL, comprising major familial melanoma research groups from North America, Europe, Asia, and Australia has created the… (More)
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Highly Cited
1999
Highly Cited
1999
Important risk factors for melanoma are densely clustered melanocytic nevi (common moles) and mutations in the p16 (CDKN2A) gene… (More)
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Review
1998
Review
1998
Since its discovery as a CDKI (cyclin-dependent kinase inhibitor) in 1993, the tumor suppressor p16 (INK4A/MTS-1/CDKN2A) has… (More)
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Highly Cited
1997
Highly Cited
1997
The biological and molecular characteristics of cell lines from metastatic melanomas have been extensively studied but less is… (More)
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Highly Cited
1996
Highly Cited
1996
The cell cycle inhibitor p16INK4a is inactivated in many human tumors and in families with hereditary melanoma and pancreatic… (More)
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Highly Cited
1995
Highly Cited
1995
THE cyclin-dependent kinase inhibitor p16 is a candidate tumour-suppressor protein that maps to a genomic locus strongly… (More)
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Highly Cited
1995
Highly Cited
1995
The p16 gene (CDKN2) which is localized on chromosome 9p21, is deleted in a significant number of sporadic cancers1–3. Moreover… (More)
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Highly Cited
1994
Highly Cited
1994
The p16 gene is located in chromosome 9p21, a region that is linked to familial melanoma and homozygously deleted in many tumour… (More)
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Highly Cited
1992
Highly Cited
1992
Linkage analysis of ten Utah kindreds and one Texas kindred with multiple cases of cutaneous malignant melanoma (CMM) provided… (More)
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Highly Cited
1978
Highly Cited
1978
Distinctive melanocytic moles are described in 37 patients from six melanoma families. Among the family members examined by the… (More)
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