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Hepatocyte Growth Factor Activator, human

Known as: HGF Activator, Hepatocyte Growth Factor Activator, EC 3.4.21.- 
Hepatocyte growth factor activator (655 aa, ~71 kDa) is encoded by the human HGFAC gene. This protein is involved in the proteolysis of single-chain… Expand
National Institutes of Health

Related topics

Related topics

11 relations
EGF-Like DomainEnzyme GeneExtracellular SpaceHGFAC gene
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Broader (1)

Serine Endopeptidases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Hepatocyte growth factor, hepatocyte growth factor activator and arginine in a rat fulminant colitis model
INTRODUCTION Dextran sodium sulfate (DSS) is commonly used to induce a murine fulminant colitis model. Hepatocyte growth factor… Expand
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Review
2014
Review
2014
Roles of HNF1α and HNF4α in pancreatic β-cells: lessons from a monogenic form of diabetes (MODY).
Mutations in the genes encoding hepatocyte nuclear factor (HNF)1α and HNF4α cause a monogenic form of diabetes mellitus known as… Expand
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2013
2013
Identification of head and neck squamous cell carcinoma biomarker candidates through proteomic analysis of cancer cell secretome.
Protein biomarker discovery for early detection of head and neck squamous cell carcinoma (HNSCC) is a crucial unmet need to… Expand
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2012
2012
Identification of hepatocyte growth factor activator (Hgfac) gene as a target of HNF1α in mouse β-cells.
HNF1α is a transcription factor that is expressed in pancreatic β-cells and mutations of the HNF1α gene cause a form of monogenic… Expand
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2010
2010
Hepatocyte growth factor activator inhibitors (HAI-1 and HAI-2) are potential targets in uterine leiomyosarcoma.
Hepatocyte growth factor activator inhibitors (HAI-1 and HAI-2) are Kunitz-type serine protease inhibitors that have a broad… Expand
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Review
2010
Review
2010
Structural and mechanistic insight into how antibodies inhibit serine proteases.
Antibodies display great versatility in protein interactions and have become important therapeutic agents for a variety of human… Expand
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2009
2009
Effect of human patient plasma ex vivo treatment on gene expression and progenitor cell activation of primary human liver cells in multi-compartment 3D perfusion bioreactors for extra-corporeal liver…
Cultivation of primary human liver cells in innovative 3D perfusion multi-compartment capillary membrane bioreactors using… Expand
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2007
2007
Hepatocyte growth factor activator inhibitor-1 (HAI-1) is essential for the integrity of basement membranes in the developing placental labyrinth.
Hepatocyte growth factor activator inhibitor-1 (HAI-1) is a membrane-associated Kunitz-type serine protease inhibitor that… Expand
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2006
2006
Role of hepatocyte growth factor activator (HGF activator) in invasive growth of human glioblastoma cells in vivo.
Hepatocyte growth factor/scatter factor (HGF/SF) is a multifunctional growth factor that is involved in invasive growth of tumor… Expand
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2001
2001
Identification of the substrates for plasma hyaluronan binding protein.
Plasma hyaluronan biding protein (PHBP) is a novel serine protease, which has an amino acid sequence homology to that of… Expand
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