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Hepatitis C, Chronic

Known as: c chronic hepatitis, hepatitis c chronic, Chronic Hepatitis C 
INFLAMMATION of the LIVER in humans that is caused by HEPATITIS C VIRUS lasting six months or more. Chronic hepatitis C can lead to LIVER CIRRHOSIS.
National Institutes of Health

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Related topics

15 relations
In BloodInterferon Alfa-2aInterferon Alfa-2bInterferon gamma-1b

Papers overview

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Highly Cited
2011
Highly Cited
2011
Telaprevir for previously untreated chronic hepatitis C virus infection.
BACKGROUND In phase 2 trials, telaprevir, a hepatitis C virus (HCV) genotype 1 protease inhibitor, in combination with… 
Highly Cited
2009
Highly Cited
2009
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
Chronic infection with hepatitis C virus (HCV) affects 170 million people worldwide and is the leading cause of cirrhosis in… 
Highly Cited
2005
Highly Cited
2005
Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C.
BACKGROUND AND AIMS Transient elastography (FibroScan; Echosens, Paris, France) is a novel, noninvasive, and rapid bedside method… 
Highly Cited
2004
Highly Cited
2004
Peginterferon-alpha2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose.
BACKGROUND Treatment with pegylated interferon (peginterferon) and ribavirin for 48 weeks is more effective than conventional… 
Highly Cited
2003
Highly Cited
2003
A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C
Information on the stage of liver fibrosis is essential in managing chronic hepatitis C (CHC) patients. However, most models for… 
Highly Cited
2002
Highly Cited
2002
Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection.
BACKGROUND Treatment with peginterferon alfa-2a alone produces significantly higher sustained virologic responses than treatment… 
Highly Cited
2001
Highly Cited
2001
Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial
Highly Cited
1998
Highly Cited
1998
Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group.
BACKGROUND Only 15 to 20 percent of patients with chronic hepatitis C have a sustained virologic response to interferon therapy… 
Highly Cited
1998
Highly Cited
1998
Binding of hepatitis C virus to CD81.
Chronic hepatitis C virus (HCV) infection occurs in about 3 percent of the world's population and is a major cause of liver… 
Review
1996
Review
1996
An algorithm for the grading of activity in chronic hepatitis C
Histological activity reflects the global assessment of basic necroinflammatory lesions and is a criterion of major importance in… 
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