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Heme Oxygenase (Decyclizing)

Known as: HSP32, Oxygenase, Haem, Heme Oxygenase 
A mixed function oxidase enzyme which during hemoglobin catabolism catalyzes the degradation of heme to ferrous iron, carbon monoxide and biliverdin… Expand
National Institutes of Health

Papers overview

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Highly Cited
2000
Highly Cited
2000
The stress-inducible protein heme oxygenase-1 provides protection against oxidative stress. The anti-inflammatory properties of… Expand
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Review
1997
Review
1997
  • M. Maines
  • Annual review of pharmacology and toxicology
  • 1997
  • Corpus ID: 34631277
The heme oxygenase (HO) system consists of two forms identified to date: the oxidative stress-inducible protein HO-1 (HSP32) and… Expand
Highly Cited
1997
Highly Cited
1997
  • K. Poss, S. Tonegawa
  • Proceedings of the National Academy of Sciences…
  • 1997
  • Corpus ID: 1884061
Stressed mammalian cells up-regulate heme oxygenase 1 (Hmox1; EC 1.14.99.3), which catabolizes heme to biliverdin, carbon… Expand
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Highly Cited
1994
Highly Cited
1994
Attack by reactive oxygen intermediates, common to many kinds of cell/tissue injury, has been implicated in the development of… Expand
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Highly Cited
1993
Highly Cited
1993
Carbon monoxide, an activator of guanylyl cyclase, is formed by the action of the enzyme heme oxygenase. By in situ hybridization… Expand
Highly Cited
1992
Highly Cited
1992
Phagocyte-mediated oxidant damage to vascular endothelium is likely involved in various vasculopathies including atherosclerosis… Expand
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Review
1988
Review
1988
  • M. Maines
  • FASEB journal : official publication of the…
  • 1988
  • Corpus ID: 22652094
In biological systems oxidation of heme is carried out by two isozymes of the microsomal heme oxygenase, HO-1 and HO-2. HO-1 is… Expand
Highly Cited
1969
Highly Cited
1969
Abstract This study characterizes microsomal heme oxygenase, a previously undescribed enzyme which catalyzes the oxidation of… Expand
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Highly Cited
1968
Highly Cited
1968
Highly Cited
1956
Highly Cited
1956
  • D. Harman
  • Journal of gerontology
  • 1956
  • Corpus ID: 42923805
The phenomenon of growth, decline and death—aging—has been the source of considerable speculation (1, 8, 10). This cycle seems to… Expand