Hematoporphyrin Photoradiation

The activities of four heme-biosynthetic enzymes, δ-aminolevulinic acid (ALA) synthase, ALA dehydratase, porphobilogen (PBG… Expand

BACKGROUND & AIMS Successful treatment in nonresectable Bismuth type III and IV cholangiocarcinoma is seldom achieved. The aim of… Expand

Abstract— The binding of hematoporphyrin derivated (Hpd) to lipid vesicles and bacterial membranes was determined by fluorescence… Expand

Hematoporphyrin derivative‐photoradiation therapy (HPD‐PRT) was used to treat choroidal melanomas in 23 human subjects. Tumor… Expand

Abstract We have used alkaline elution to study DNA damage produced by the photosensitizer hematoporphyrin derivative (HPD) in… Expand

Rat liver microsomal cytochrome P‐450 undergoes rapid destruction in the presence of hematoporphyrin derivative (HpD) and solar… Expand

Hematoporphyrin derivative‐photoradiation therapy (HPD‐PRT) of human malignancy has been performed on 267 tumor sites in 50… Expand

The induction and repair of alkali labile lesions and single strand breaks in DNA of CHO cells following HpD photoradiation of X… Expand

Four hundred eighteen patients were treated with oral photochemotherapy up to 5 years and monitored regularly for the occurrence… Expand

The oxygen-dependent photooxidation of NADPH in the presence of hematoporphyrin in D2O results in the production of enzymatically… Expand