Heat-Shock Proteins 70

Known as: 70-kDa Heat Shock Protein, HSP-70, Heat Shock Protein 70 
A class of MOLECULAR CHAPERONES found in both prokaryotes and in several compartments of eukaryotic cells. These proteins can interact with… (More)
National Institutes of Health

Related topics

Related topics

26 relations
150 kDa oxygen-regulated proteinCellular Stress ResponseHSPA4 geneHeat Shock 70 kDa Protein 1A/1B
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Narrower (8)

GrpS protein, Myxococcus xanthusHSPA12B protein, ratHSPA9 protein, humanKAR2 protein, yeast
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Broader (1)

Heat shock proteins

Papers overview

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Highly Cited
2009
Highly Cited
2009
A small molecule inhibitor of inducible heat shock protein 70.
The multifunctional, stress-inducible molecular chaperone HSP70 has important roles in aiding protein folding and maintaining… (More)
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Highly Cited
2006
Highly Cited
2006
Heat shock proteins 70 and 90 inhibit early stages of amyloid beta-(1-42) aggregation in vitro.
Alzheimer disease is a neurological disorder that is characterized by the presence of fibrils and oligomers composed of the… (More)
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Highly Cited
2004
Highly Cited
2004
Heat Shock Protein 70 Promotes Cell Survival by Inhibiting Lysosomal Membrane Permeabilization
Heat shock protein 70 (Hsp70) is a potent survival protein whose depletion triggers massive caspase-independent tumor cell death… (More)
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Review
2002
Review
2002
Interaction of heat shock proteins with peptides and antigen presenting cells: chaperoning of the innate and adaptive immune responses.
Heat shock proteins are abundant soluble intracellular proteins, present in all cells. Members of the heat shock protein family… (More)
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Highly Cited
2002
Highly Cited
2002
Heat-shock proteins as activators of the innate immune system.
Peptides bound or linked to heat-shock proteins (HSPs) of microbial or mammalian origin have been shown to elicit potent antigen… (More)
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Highly Cited
2000
Highly Cited
2000
A small heat shock protein cooperates with heat shock protein 70 systems to reactivate a heat-denatured protein.
Small heat shock proteins (sHsps) are a diverse group of heat-induced proteins that are conserved in prokaryotes and eukaryotes… (More)
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Highly Cited
1997
Highly Cited
1997
Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-alpha-induced apoptosis by inducing heat shock protein 70 expression.
Nitric oxide (NO) and tumor necrosis factor-alpha (TNFalpha) play important roles in the pathogenesis of liver disease during… (More)
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Highly Cited
1993
Highly Cited
1993
Heat shock protein 70-associated peptides elicit specific cancer immunity
Vaccination of mice with heat shock protein 70 (hsp70) preparations derived from the Meth A sarcoma, but not from normal tissues… (More)
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Highly Cited
1990
Highly Cited
1990
Interaction of Hsp 70 with newly synthesized proteins: implications for protein folding and assembly.
The 70-kilodalton family of heat shock proteins (Hsp 70) has been implicated in posttranslational protein assembly and… (More)
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Review
1988
Review
1988
The heat-shock proteins.
PERSPECTIVES ANDUMMARY .............................................................. 632 HSP110… (More)
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