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Hafnium Oxide-containing Nanoparticles NBTXR3

Known as: NBTXR3 
A suspension of nanoparticles containing inert inorganic hafnium oxide (HfO2) crystals with potential antineoplastic activity. Upon injection of… Expand
National Institutes of Health

Papers overview

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2020
2020
Purpose Despite tremendous results achieved by immune checkpoint inhibitors, most patients are not responders, mainly because of… Expand
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Review
2019
Review
2019
BACKGROUND Pathological complete response to preoperative treatment in adults with soft-tissue sarcoma can be achieved in only a… Expand
2019
2019
The cGAS-STING pathway can be activated by radiation induced DNA damage and because of its important role in anti-cancer immunity… Expand
2019
2019
6069Background: New therapeutic approaches are needed for elderly or frail head and neck squamous cell carcinoma (HNSCC) patients… Expand
Review
2018
Review
2018
Radiotherapy is one of the major therapeutic strategies for cancer treatment. In the past decade, there has been growing interest… Expand
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Highly Cited
2016
Highly Cited
2016
Purpose: This phase I study aimed to determine the recommended dose (RD), safety profile, and feasibility of a procedure… Expand
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2016
2016
Purpose: This phase I study aimed to determine the recommended dose (RD), safety profile, and feasibility of a procedure… Expand
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Highly Cited
2014
Highly Cited
2014
BackgroundHafnium oxide, NBTXR3 nanoparticles were designed for high dose energy deposition within cancer cells when exposed to… Expand
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Review
2014
Review
2014
Since the discovery of cisplatin about 40 years ago, the design of innovative metal-based anticancer drugs is a growing area of… Expand
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2014
2014
10563 Background: Functionalized hafnium oxide nanoparticles (NBTXR3) have been developed as selective radioenhancers, which may… Expand