HTRA1 gene

Known as: HtrA Serine Peptidase 1 Gene, HtrA, E. COLI, HOMOLOG OF, PRSS11 
This gene plays a role in proteolysis.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
BACKGROUND The genetic cause of cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy… (More)
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Highly Cited
2007
Highly Cited
2007
Genetic variants at chromosomes 1q31-32 and 10q26 are strongly associated with susceptibility to age-related macular degeneration… (More)
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Highly Cited
2007
Highly Cited
2007
PURPOSE To investigate whether variants in the LOC387715 locus and the HtrA serine peptidase 1 (HTRA1) gene within the 10q26… (More)
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Highly Cited
2006
Highly Cited
2006
Age-related macular degeneration (AMD), the most common cause of irreversible vision loss in individuals aged older than 50 years… (More)
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Highly Cited
2006
Highly Cited
2006
Age-related macular degeneration (AMD) is the most common cause of irreversible vision loss in the developed world and has a… (More)
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Highly Cited
2005
Highly Cited
2005
On the basis of genomewide linkage studies of families affected with age-related maculopathy (ARM), we previously identified a… (More)
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Highly Cited
2004
Highly Cited
2004
HtrA1, a member of the mammalian HtrA serine protease family, has a highly conserved protease domain followed by a PDZ domain… (More)
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Highly Cited
2004
Highly Cited
2004
We report here that HtrA1, a candidate tumor suppressor, is downregulated in ovarian cancer. Expression of HtrA1 is downregulated… (More)
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Highly Cited
2002
Highly Cited
2002
Inhibitor of apoptosis (IAP) proteins inhibit caspases, a function counteracted by IAP antagonists, insect Grim, HID, and Reaper… (More)
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Highly Cited
2002
Highly Cited
2002
Differential gene expression of cell lines derived from a malignant melanoma or its autologous lymph node metastasis using cDNA… (More)
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