HSP90 inhibitor CNF2024

Known as: Hsp90 Antagonist CNF2024, Hsp90 Inhibitor BIIB021 
An orally active inhibitor of heat shock protein 90 (HSP90) with potential antineoplastic activity. HSP90, a chaperon protein upregulated in a… (More)
National Institutes of Health

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Topic mentions per year

2004-2018
012320042018

Papers overview

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2017
2017
BACKGROUND/AIMS Acetaminophen (APAP) refers to a medication used to manage pain and fever symptoms. Heat shock protein 90 (Hsp90… (More)
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2016
2016
Pathogen components, such as lipopolysaccharides of Gram-negative bacteria that activate Toll-like receptor 4, induce mitogen… (More)
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2015
2015
Human Hsp90 isoforms are molecular chaperones that are often up-regulated in malignances and represent a primary target for Hsp90… (More)
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2014
2014
BACKGROUND We previously reported that radicicol (Hsp90 inhibitor) induced a reduction in the renal blood flow and glomerular… (More)
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2013
2013
BACKGROUND HSP90 inhibition leads to proteosomal degradation of activated KIT and has in vitro activity against gastrointestinal… (More)
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2013
2013
The increasing use of fragment-based lead discovery (FBLD) in industry as well as in academia creates a high demand for sensitive… (More)
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2013
2013
Previous in vitro studies indicated that aldosterone nongenomically phosphorylates epidermal growth factor receptor (EGFR… (More)
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2011
2011
Five host cellular proteins were identified in the secretion medium from Japanese encephalitis virus (JEV)-infected baby hamster… (More)
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2010
2010
Prostate cancer progression to the androgen-independent (AI) state involves acquisition of pathways that allow tumor growth under… (More)
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2006
2006
The functions of molecular chaperones have been extensively investigated biochemically in vitro and genetically in bacteria and… (More)
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