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HSD3B2 wt Allele

Known as: HSDB, Hydroxy-Delta-5-Steroid Dehydrogenase, 3 Beta- and Steroid Delta-Isomerase wt Allele, HSDB3B 
Human HSD3B2 wild-type allele is located in the vicinity of 1p13.1 and is approximately 8 kb in length. This allele, which encodes 3 beta… Expand
National Institutes of Health

Papers overview

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2019
2019
Leydig cells play a pivotal function in the synthesis of a male sex steroid, testosterone. The ability of the steroid production… Expand
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2015
2015
HSD3B catalyzes the synthesis of δ4 steroids such as progesterone in the adrenals and gonads. Individuals lacking HSD3B2 activity… Expand
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2014
2014
The aim of the study was to investigate the in vitro effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on steroid hormone… Expand
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2012
2012
So where is the excitement in the study of steroidogenesis? It is pretty well cut-and-dried; after all, 17b-estradiol is the same… Expand
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2010
2010
  • B. Zirkin
  • Biology of reproduction
  • 2010
  • Corpus ID: 39700997
Testosterone-producing adult Leydig cells emerge at puberty, and most persist thereafter without turning over. But where do the… Expand
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2004
2004
To test our hypothesis that the hormonal phenotype of mild 3beta-hydroxysteroid dehydrogenase (HSD3B) deficiency in… Expand
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Highly Cited
2002
Highly Cited
2002
3beta-hydroxysteroid dehydrogenases (HSD3Bs), encoded by the HSD3B gene family at 1p13, have long been hypothesized to have a… Expand
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2000
2000
Mutations in HSD3B2, the gene for 3beta-hydroxysteroid dehydrogenase type II (3beta-HSD II) have been detected and activities… Expand
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1995
1995
The enzyme 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase (3 beta-HSD) catalyses an essential step in the… Expand
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1991
1991
Polymorphism: Sequencing of amplified exon 4(1) identified a single base pair substitution at position 1100 in the coding… Expand
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