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HSD3B2 wt Allele

Known as: HSDB, Hydroxy-Delta-5-Steroid Dehydrogenase, 3 Beta- and Steroid Delta-Isomerase wt Allele, HSDB3B 
Human HSD3B2 wild-type allele is located in the vicinity of 1p13.1 and is approximately 8 kb in length. This allele, which encodes 3 beta… 
National Institutes of Health

Related topics

Related topics

4 relations
1p13.1Oxidation-ReductionSteroid Metabolic Process

Broader (1)

HSD3B2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Three populations of adult Leydig cells in mouse testes revealed by a novel mouse HSD3B1-specific rat monoclonal antibody.
2015
2015
Two Zebrafish hsd3b Genes Are Distinct in Function, Expression, and Evolution.
HSD3B catalyzes the synthesis of δ4 steroids such as progesterone in the adrenals and gonads. Individuals lacking HSD3B2 activity… 
2014
2014
Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on secretion of steroids and STAR, HSD3B and CYP19A1 mRNA expression in chicken ovarian follicles.
2012
2012
Of the Many Secrets of Steroidogenesis
So where is the excitement in the study of steroidogenesis? It is pretty well cut-and-dried; after all, 17b-estradiol is the same… 
2010
2010
Where Do Adult Leydig Cells Come From?1
  • B. Zirkin
  • Biology of Reproduction
  • 2010
  • Corpus ID: 39700997
Testosterone-producing adult Leydig cells emerge at puberty, and most persist thereafter without turning over. But where do the… 
Highly Cited
2004
Highly Cited
2004
The hormonal phenotype of Nonclassic 3 beta-hydroxysteroid dehydrogenase (HSD3B) deficiency in hyperandrogenic females is associated with insulin-resistant polycystic ovary syndrome and is not a…
To test our hypothesis that the hormonal phenotype of mild 3beta-hydroxysteroid dehydrogenase (HSD3B) deficiency in… 
Highly Cited
2002
Highly Cited
2002
Joint effect of HSD3B1 and HSD3B2 genes is associated with hereditary and sporadic prostate cancer susceptibility.
3beta-hydroxysteroid dehydrogenases (HSD3Bs), encoded by the HSD3B gene family at 1p13, have long been hypothesized to have a… 
2000
2000
Phenotypic variability and origins of mutations in the gene encoding 3beta-hydroxysteroid dehydrogenase type II.
Mutations in HSD3B2, the gene for 3beta-hydroxysteroid dehydrogenase type II (3beta-HSD II) have been detected and activities… 
1995
1995
Genetic linkage mapping of HSD3B1 and HSD3B2 encoding human types I and II 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase close to D1S514 and the centromeric D1Z5 locus.
The enzyme 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase (3 beta-HSD) catalyses an essential step in the… 
1991
1991
Non-synonymous polymorphism in the coding sequence of human 3-beta hydroxysteroid dehydrogenase (HSD3B).
Polymorphism: Sequencing of amplified exon 4(1) identified a single base pair substitution at position 1100 in the coding… 
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