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HS6ST2 protein, human

Known as: Heparan-Sulfate 6-O-Sulfotransferase 2, HS6ST-2, heparan sulfate 6-O-sulfotransferase 2 protein, human 
Heparan-sulfate 6-O-sulfotransferase 2 (605 aa, ~69 kDa) is encoded by the human HS6ST2 gene. This protein plays a role in the sulfation of… Expand
National Institutes of Health

Related topics

Related topics

4 relations
Enzyme GeneHS6ST2 geneHeparan Sulfate Biosynthesissulfotransferase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Ovarian Cancer Cell Heparan Sulfate 6-O-Sulfotransferases Regulate an Angiogenic Program Induced by Heparin-binding Epidermal Growth Factor (EGF)-like Growth Factor/EGF Receptor Signaling
Background: Numerous angiogenic growth factors depend on heparan sulfate for their activity. Results: Heparan sulfate 6-O… Expand
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Highly Cited
2012
Highly Cited
2012
Endothelial Heparan Sulfate 6-O-Sulfation Levels Regulate Angiogenic Responses of Endothelial Cells to Fibroblast Growth Factor 2 and Vascular Endothelial Growth Factor*
Background: Heparan sulfate (HS) is an essential regulator of multiple angiogenic growth factors. Results: Down-regulation of 6-O… Expand
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2012
2012
Heparan Sulfate 6-O-Sulfotransferase Isoform-dependent Regulatory Effects of Heparin on the Activities of Various Proteases in Mast Cells and the Biosynthesis of 6-O-Sulfated Heparin*
Background: Heparin regulates mast cell proteases. Results: Both HS6ST-1 and HS6ST-2 are involved in 6-O-sulfation of heparin… Expand
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2010
2010
Functional analysis of chick heparan sulfate 6‐O‐sulfotransferases in limb bud development
Heparan sulfate (HS) interacts with numerous growth factors, morphogens, receptors, and extracellular matrix proteins. Disruption… Expand
Review
2010
Review
2010
Mice deficient in heparan sulfate 6-O-sulfotransferase-1.
Heparan sulfate chains are initially synthesized on core proteins as linear polysaccharides composed of glucuronic acid-N… Expand
Highly Cited
2005
Highly Cited
2005
A unique role for 6-O sulfation modification in zebrafish vascular development.
Heparan sulfate proteoglycans are important modulators of growth factor signaling in a variety of patterning processes. Secreted… Expand
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Highly Cited
2004
Highly Cited
2004
Distinctive Expression Patterns of Heparan Sulfate O-Sulfotransferases and Regional Differences in Heparan Sulfate Structure in Chick Limb Buds*
The skeletal tissue development and patterning in chick limb buds are known to be under the spacio-temporal control of various… Expand
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Highly Cited
2003
Highly Cited
2003
Biosynthesis of heparan sulphate with diverse structures and functions: two alternatively spliced forms of human heparan sulphate 6-O-sulphotransferase-2 having different expression patterns and…
Heparan sulphate 6- O -sulphotransferase (HS6ST) catalyses the transfer of sulphate from adenosine 3'-phosphate, 5… Expand
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Highly Cited
2000
Highly Cited
2000
The Occurrence of Three Isoforms of Heparan Sulfate 6-O-Sulfotransferase Having Different Specificities for Hexuronic Acid Adjacent to the TargetedN-Sulfoglucosamine*
We previously cloned heparan sulfate 6-O-sulfotransferase (HS6ST) (Habuchi, H., Kobayashi, M., and Kimata, K. (1998) J. Biol… Expand
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