HRK gene

Known as: DP5, Harakiri Gene, harakiri, BCL2 interacting protein 
This gene plays a role in apoptotic activation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1978-2017
051019782017

Papers overview

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2014
2014
Programmed cell death protein 5 (PDCD5) has been proposed to act as a pro-apoptotic factor and tumor suppressor. However, the… (More)
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2012
2012
Environmental factors such as diets rich in saturated fats contribute to dysfunction and death of pancreatic β-cells in diabetes… (More)
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Highly Cited
2009
Highly Cited
2009
Chronic inflammation and pro-inflammatory cytokines are important mediators of pancreatic β-cell destruction in type 1 diabetes… (More)
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2007
2007
The pro-apoptotic BH3-only members of the Bcl2 family, crucial initiators of cell death, are activated by a diverse array of… (More)
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2005
2005
Polyamidoamine (PAMAM) dendrimer represents one of the most efficient polymeric gene carriers. To investigate the effect of the… (More)
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2005
2005
To detect and identify the genetic alterations and methylation status of the HRK gene in human glioblastomas, we analyzed a… (More)
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2005
2005
Growing evidence suggests that cells undergo apoptosis after spinal cord injury (SCI). However, little is known about the early… (More)
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2003
2003
A pancreatic adenocarcinoma cell line (Paca44) was treated with trichostatin-A (TSA), a potent inhibitor of histone deacetylases… (More)
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1999
1999
DP5, which contains a BH3 domain, was cloned as a neuronal apoptosis-inducing gene. To confirm that DP5 interacts with members of… (More)
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Highly Cited
1997
Highly Cited
1997
To study the molecular mechanisms underlying neuronal programmed cell death (PCD), we performed differential display screening… (More)
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