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HRAS gene targeted mutation analysis:Prid:Pt:Bone mar:Nom:Molgen

Known as: HRAS gene mutations found [Identifier] in Bone marrow by Molecular genetics method Nominal, HRAS, gene , analisi di mutazione mirata:Prid:Pt:Mid oss:Nom:Molgen, HRAS geni Mutasyon analizi:MevcKimlik:Zml?:Kem il:Snf:Molgen 
National Institutes of Health

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Bone MarrowGene MutationGenesHRAS gene

Papers overview

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2020
2020
Fetal Costello syndrome: description of phenotype of HRAS exon 1 mutations
This is a description of similar prenatal ultrasound findings in five cases of fetal Costello syndrome from 3 countries. We… 
2018
2018
Abstract PD4-13: Estrogen receptor-negative breast adenomyoepitheliomas are driven by co-occurring HRAS hotspot and PI3K pathway gene mutations: A genetic and functional analysis
Introduction:Adenomyoepithelioma (AME) of the breast is a rare biphasic tumor, characterized by epithelial and myoepithelial… 
2016
2016
Phase I study of QLNC120, a novel EGFR and HER2 kinase inhibitor, in pre-treated patients with HER2-overexpressing advanced breast cancer
This study evaluated the dose-limiting toxicities (DLT), maximum tolerated dose (MTD), pharmacokinetic profile, and preliminary… 
Highly Cited
2015
Highly Cited
2015
Comprehensive assessment of cancer missense mutation clustering in protein structures
Significance Tumor sequencing efforts have enabled the identification of cancer genes based on an excess of mutations in the gene… 
2015
2015
Противоположные ассоциации мутаций генов HRAS и KRAS с клиническими параметрами рака мочевого пузыря
HRAS, KRAS and NRAS gene products belong to the superfamily of small GTPases. These proteins regulate cellular response to… 
2013
2013
Kinetic mechanisms of mutation-dependent Harvey Ras activation and their relevance for the development of Costello syndrome.
Costello syndrome is linked to activating mutations of a residue in the p-loop or the NKCD/SAK motifs of Harvey Ras (HRas). More… 
2006
2006
Advances in Brief Systematic HRAS Amplification in Ovary-independent Mammary Tumors : Correlation with Progressively Anaplastic Phenotypes 1
Progression of well differentiated rat mammary adenocarcinomas to very anaplastic phenotypes was found to correlate with a… 
1997
1997
Delineation of the centromeric and telomeric chromosome segment 11p15.5 lung cancer suppressor regions LOH11A and LOH11B
We have reported frequent allele loss for two separate regions identified by the markers D11S12 and HRAS on chromosome 11p15.5… 
1993
1993
HRAS protooncogene polymorphism and breast cancer.
The potential association of polymorphism in the HRAS protooncogene variable repeat region with susceptibility to cancer has… 
1992
1992
Deletion of chromosome 11p13-11p15.5 sequences in invasive human ovarian cancer is a subclonal progression factor.
In human ovarian cancer, multiple specific chromosomal deletions can be found by cytogenetic analysis or molecular techniques… 
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