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HOXB13 protein, human

Known as: HOXB13, Hoxb-13 protein, human, Homeobox Protein Hox-B13 
Homeobox protein Hox-B13 (284 aa, ~31 kDa) is encoded by the human HOXB13 gene. This protein is involved in both transcriptional regulation and… Expand
National Institutes of Health

Related topics

Related topics

10 relations
Androgen Receptor Regulation PathwayCell NucleusDNA-Binding ProteinsGenes, Regulator
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
HOXB13 expression and promoter methylation as a candidate biomarker in gastric cancer.
Homeobox b13 (HOXB13) is considered to be a tumor suppressor gene in multiple types of human cancer. The present study aimed to… Expand
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2018
2018
Oncoprotein HBXIP enhances HOXB13 acetylation and co-activates HOXB13 to confer tamoxifen resistance in breast cancer
BackgroundResistance to tamoxifen (TAM) frequently occurs in the treatment of estrogen receptor positive (ER+) breast cancer… Expand
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2014
2014
HOXB13 contributes to G1/S and G2/M checkpoint controls in prostate
HOXB13 is a homeobox protein that is expressed in normal adult prostate and colon tissues; however, its deregulated expression… Expand
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2010
2010
Predictive relevance of HOXB13 protein expression for tamoxifen benefit in breast cancer
IntroductionThe HOXB13:IL17BR index has been identified to predict clinical outcome in the setting of adjuvant tamoxifen… Expand
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2010
2010
HOXB13 promotes androgen independent growth of LNCaP prostate cancer cells by the activation of E2F signaling
BackgroundAndrogen signaling plays a critical role in the development of prostate cancer and its progression. However, androgen… Expand
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Highly Cited
2009
Highly Cited
2009
The homeodomain protein HOXB13 regulates the cellular response to androgens.
HOXB13 is a member of the homeodomain family of sequence-specific transcription factors and, together with the androgen receptor… Expand
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Highly Cited
2007
Highly Cited
2007
HOXB13 promotes ovarian cancer progression.
Deregulated expression of HOXB13 in a subset of estrogen receptor-positive breast cancer patients treated with tamoxifen… Expand
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Highly Cited
2007
Highly Cited
2007
The prognostic biomarkers HOXB13, IL17BR, and CHDH are regulated by estrogen in breast cancer.
PURPOSE We previously identified three genes, HOXB13, IL17BR, and CHDH, that strongly predict clinical outcome in estrogen… Expand
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Highly Cited
2005
Highly Cited
2005
HOXB13 is downregulated in colorectal cancer to confer TCF4-mediated transactivation
Mutations in the Wnt signalling cascade are believed to cause aberrant proliferation of colorectal cells through T-cell factor-4… Expand
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Highly Cited
2004
Highly Cited
2004
HOXB13 induces growth suppression of prostate cancer cells as a repressor of hormone-activated androgen receptor signaling.
Androgen receptor (AR) signals play a decisive role in regulating the growth and differentiation of both normal and cancerous… Expand
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