FAQ

HOXB13 protein, human

Known as: HOXB13, Hoxb-13 protein, human, Homeobox Protein Hox-B13 
Homeobox protein Hox-B13 (284 aa, ~31 kDa) is encoded by the human HOXB13 gene. This protein is involved in both transcriptional regulation and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2005-2018
012320052018

Related topics

Related topics

10 relations
Androgen Receptor Regulation PathwayCell NucleusDNA-Binding ProteinsGenes, Regulator
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Broader (1)

Homeodomain Proteins

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
HOXB13 protein, human
Cell Nucleus
Transcriptional Regulation
dna binding
Genes, Regulator
Homeodomain Proteins

Papers overview

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2018
2018
Oncoprotein HBXIP enhances HOXB13 acetylation and co-activates HOXB13 to confer tamoxifen resistance in breast cancer
BACKGROUND Resistance to tamoxifen (TAM) frequently occurs in the treatment of estrogen receptor positive (ER+) breast cancer… (More)
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2014
2014
HOXB13 downregulates intracellular zinc and increases NF-κB signaling to promote prostate cancer metastasis
Characteristically, prostate cancer (PCa) cells exhibit marked decrease in intracellular zinc; however, the mechanism responsible… (More)
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2014
2014
HOXB13 regulates the prostate-derived Ets factor: implications for prostate cancer cell invasion.
HOXB13 has been shown to enhance the invasive potential of breast and endometrial tumors. HOXB13 is also abundant in castration… (More)
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2012
2012
ATRA Inhibits the Proliferation of DU145 Prostate Cancer Cells through Reducing the Methylation Level of HOXB13 Gene
All-trans retinoic acid (ATRA) has been widely investigated for treatments of many cancers including prostate cancer. HOXB13… (More)
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2010
2010
Predictive relevance of HOXB13 protein expression for tamoxifen benefit in breast cancer
The HOXB13:IL17BR index has been identified to predict clinical outcome in the setting of adjuvant tamoxifen monotherapy of… (More)
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2010
2010
HOXB13 is co-localized with androgen receptor to suppress androgen-stimulated prostate-specific antigen expression
During the prostate cancer (PCa) development and its progression into hormone independency, androgen receptor (AR) signals play a… (More)
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2009
2009
Recruitment of HDAC4 by transcription factor YY1 represses HOXB13 to affect cell growth in AR-negative prostate cancers.
HOXB13 is a homeodomain protein implicated to play a role in growth arrest in AR (androgen receptor)-negative prostate cancer… (More)
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2007
2007
HOXB13 promotes ovarian cancer progression.
Deregulated expression of HOXB13 in a subset of estrogen receptor-positive breast cancer patients treated with tamoxifen… (More)
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2005
2005
HOXB13 is downregulated in colorectal cancer to confer TCF4-mediated transactivation
Mutations in the Wnt signalling cascade are believed to cause aberrant proliferation of colorectal cells through T-cell factor-4… (More)
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2005
2005
Hoxb13 up-regulates transglutaminase activity and drives terminal differentiation in an epidermal organotypic model.
Hox genes act to differentiate and pattern embryonic structures by promoting the proliferation of specific cell types. An… (More)
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