HOLOPROSENCEPHALY 2 (disorder)

Known as: HOLOPROSENCEPHALY 2, HPE2, Holoprosencephaly Type 2 
A rare disorder characterized by the partial separation of the cerebral hemispheres. It is associated with mutations in the SIX3 gene.
National Institutes of Health

Papers overview

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2004
2004
Holoprosencephaly (HPE) is a relatively common brain malformation resulting in an incomplete separation of the two cerebral… (More)
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2001
2001
Hypericum perforatum extracts (HPE) inhibit ethanol intake in rats. Hypericin and hyperforin have been proposed as major active… (More)
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2000
2000
Holoprosencephaly (HPE) is a severe brain malformation which results from incomplete cleavage of the forebrain during early… (More)
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Highly Cited
1999
Highly Cited
1999
Holoprosencephaly (HPE) is a common, severe malformation of the brain that involves separation of the central nervous system into… (More)
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Highly Cited
1999
Highly Cited
1999
The Drosophila gene sine oculis (so), a nuclear homeoprotein that is required for eye development, has several homologues in… (More)
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1996
1996
Holoprosencephaly (HPE) is a common developmental defect involving the brain and face in humans. Cytogenetic deletions in… (More)
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Highly Cited
1995
Highly Cited
1995
The Drosophila sine oculis homeobox-containing gene is known to play an essential role in controlling the initial events of… (More)
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1995
1995
A 2-year-old girl with alobar holoprosencephaly associated with facial abnormalities, central diabetes insipidus, and a neuronal… (More)
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1983
1983
Two stillborn sisters had characteristics of both agnathia and holoprosencephaly. Familial occurrence implies that agnathia… (More)
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