HMGB1 gene

Known as: HIGH MOBILITY GROUP BOX 1, High-Mobility Group Box 1 Gene, SBP-1 
This gene plays a role in chromatin remodeling, signal transduction and the regulation of gene transcription. It is also involved in the pro… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
High mobility group box 1 (HMGB1) is a nuclear protein with extracellular inflammatory cytokine activity. It is released… (More)
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Highly Cited
2010
Highly Cited
2010
Autophagy clears long-lived proteins and dysfunctional organelles and generates substrates for adenosine triphosphate production… (More)
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Review
2010
Review
2010
High mobility group box 1 (HMGB1), a highly conserved, ubiquitous protein present in the nuclei and cytoplasm of nearly all cell… (More)
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Highly Cited
2010
Highly Cited
2010
Endotoxin administration recapitulates many of the host responses to sepsis. Inhibitors of the cysteine protease caspase 1 have… (More)
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Highly Cited
2008
Highly Cited
2008
In ischemic stroke, the necrotic core is surrounded by a zone of inflammation, in which delayed cell death aggravates the initial… (More)
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Highly Cited
2007
Highly Cited
2007
High mobility group box 1 (HMGB1) can be actively secreted by macrophages/monocytes in response to exogenous and endogenous… (More)
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Highly Cited
2007
Highly Cited
2007
Tissue damage is usually followed by healing, as both differentiated and stem cells migrate to replace dead or damaged cells… (More)
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Highly Cited
2004
Highly Cited
2004
High mobility group box 1 (HMGB1) is an abundant chromatin protein that acts as a cytokine when released in the extracellular… (More)
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Highly Cited
2004
Highly Cited
2004
High mobility group box 1 (HMGB1) protein, originally described as a DNA-binding protein that stabilizes nucleosomes and… (More)
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Highly Cited
2004
Highly Cited
2004
Despite significant advances in intensive care therapy and antibiotics, severe sepsis accounts for 9% of all deaths in the United… (More)
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