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Wnt/β-catenin signaling plays an essential role in blood-brain barrier (BBB) formation and maintenance under pathophysiological… Expand Neuronal apoptosis is one of the essential mechanisms of early brain injury after subarachnoid hemorrhage (SAH). Recently, HLY78… Expand The health-related effects of ionizing radiation on embryonic development and their underlying mechanisms are still unclear. The… Expand Phenanthridine derivativeHLY78 has previously been identified as the first Wnt/β-catenin signalling pathway agonist that targets… Expand Previously, HLY78, a lycorine derivative, was identified as the first Wnt/β-catenin signaling agonist through binding to the DAX… Expand Gastric cancer (GC) is the third leading cause of cancer-related mortality worldwide. Oxysterol-binding protein-related protein 8… Expand Multiple factors including tumor heterogeneity and intrinsic or acquired resistance have been associated with drug resistance in… Expand BACKGROUND
Resveratrol is a dietary compound that has been widely reported for its anticancer activities. However, successful… Expand Lycorine is a benzylphenethylamine-type alkaloid member of the Amaryllidaceae family. A lycorine derivative, HLY78, was… Expand The Wnt/β-catenin signaling pathway has a crucial role in embryonic development, stem cell maintenance and human disease. By… Expand