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Aim/hypothesisType 1 diabetes (T1D) is an autoimmune disease with multiple susceptibility genes. The aim of this study was to… Expand Diabetes-prone (DP) BB rats spontaneously develop insulin-dependent diabetes resembling human type 1 diabetes. They also exhibit… Expand The major histocompatibility complex (MHC) HLA region on chromosome 6p21 contains the major locus of type 1 diabetes (IDDM1… Expand IDDM is a T-cell-mediated autoimmune disease depending on both genetic and environmental susceptibility factors. The HLA class II… Expand Genome-wide scans for linkage of chromosome regions to type 1 diabetes in affected sib pair families have revealed that the major… Expand Susceptibility to autoimmune insulin-dependent (type 1) diabetes mellitus is determined by a combination of environmental and… Expand Genome-wide scans for linkage of chromosome regions to type 1 diabetes in affected sib pair families have revealed that the major… Expand To investigate the genetic component of multifactorial diseases such as type 1 (insulin-dependent) diabetes mellitus (IDDM… Expand Whole genome linkage analysis of type 1 diabetes using affected sib pair families and semi-automated genotyping and data capture… Expand We have searched the human genome for genes that predispose to type 1 (insulin-dependent) diabetes mellitus using semi-automated… Expand