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HL 725

Known as: HL-725 
National Institutes of Health

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Papers overview

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2009
2009
A Cell-Based β-Lactamase Reporter Gene Assay for the CREB Signaling Pathway
The Cyclic-AMP Response Element Binding (CREB) proteins comprise a family of transcription factors that stimulate or repress the… 
2000
2000
Role of phosphodiesterase and protein kinase G on nitric oxide-induced inhibition of prolactin release from the rat anterior pituitary.
OBJECTIVE In order to determine the mechanism by which nitric oxide (NO) inhibits prolactin release, we investigated the… 
1994
1994
Atrial Natriuretic Peptide Reduces Cyclic AMP by Activating Cyclic GMP‐Stimulated Phosphodiesterase in Vascular Endothelial Cells
Summary Bovine aortic endothelial cells contain cyclic GMP-stimulated phosphodiesterase (PDE) regulating in-tracellular cyclic… 
Highly Cited
1991
Highly Cited
1991
Phosphodiesterase II, the cGMP-activatable cyclic nucleotide phosphodiesterase, regulates cyclic AMP metabolism in PC12 cells.
Analysis of cyclic nucleotide phosphodiesterase (PDE) activity in cellular fractions from cultured rat pheochromocytoma (PC12… 
1987
1987
Cyclic nucleotide phosphodiesterase inhibitors prevent aggregation of human platelets by raising cyclic AMP and reducing cytoplasmic free calcium mobilization.
1987
1987
Role of plasma adenosine in the antiplatelet action of HL 725, a potent inhibitor of cAMP phosphodiesterase: species differences.
1987
1987
Comparison of the effects of a thromboxane synthase inhibitor or prostacyclin in combination with a phosphodiesterase inhibitor for prevention of experimental thrombosis and sudden death in rabbits.
This study was designed to determine the in vivo effects of a phosphodiesterase inhibitor (HL 725) in combination with a… 
Highly Cited
1982
Highly Cited
1982
HL 725, an extremely potent inhibitor of platelet phosphodiesterase and induced platelet aggregation in vitro.
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