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HIPK2 protein, human

Known as: homeodomain interacting protein kinase 2, human, Homeodomain-Interacting Protein Kinase 2, Homeodomain Interacting Protein Kinase 2 
Homeodomain-interacting protein kinase 2 (1198 aa, ~131 kDa) is encoded by the human HIPK2 gene. This protein plays a role in protein phosphorylation… Expand
National Institutes of Health

Papers overview

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2016
2016
Persistent accumulation of misfolded proteins causes endoplasmic reticulum (ER) stress, a prominent feature in many… Expand
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Highly Cited
2013
Highly Cited
2013
In response to intense stress, the tumor protein p53 (p53) tumor suppressor rapidly mounts a direct mitochondrial death program… Expand
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Highly Cited
2011
Highly Cited
2011
Wnt pathways play essential roles in cell proliferation, morphogenesis, and cell fate specification during embryonic development… Expand
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Review
2010
Review
2010
p53 transcriptional activity depends mainly on posttranslational modifications and protein/protein interaction. Another important… Expand
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Highly Cited
2006
Highly Cited
2006
Sumoylation serves to control key cellular functions, but the regulation of SUMO E3 ligase activity is largely unknown. Here we… Expand
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2006
2006
SALL1 is a member of the SAL gene family that encodes a group of putative developmental transcription factors. SALL1 plays a… Expand
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2005
2005
The HIPK2 protein is a critical regulator of apoptosis and functionally interacts with p53 to increase gene expression. Here we… Expand
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2005
2005
The modification of homeodomain-interacting protein kinase 2 (HIPK2) by small ubiquitin-like modifier 1 (SUMO-1) plays an… Expand
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2002
2002
Using the yeast two-hybrid system, we have identified the Ran-binding protein (RanBPM) as an interaction partner of homeodomain… Expand
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Highly Cited
1999
Highly Cited
1999
Posttranslational modifications such as ubiquitination and phosphorylation play an important role in the regulation of cellular… Expand
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