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HIPK2 protein, human
Known as:
homeodomain interacting protein kinase 2, human
, Homeodomain-Interacting Protein Kinase 2
, Homeodomain Interacting Protein Kinase 2
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Homeodomain-interacting protein kinase 2 (1198 aa, ~131 kDa) is encoded by the human HIPK2 gene. This protein plays a role in protein phosphorylation…
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National Institutes of Health
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Related topics
Related topics
13 relations
Broader (2)
Carrier Proteins
Protein-Serine-Threonine Kinases
Cell Cycle Control
Cell Nucleus
Enzyme Gene
HIPK2 gene
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis
Sebum Lee
,
Yulei Shang
,
+16 authors
E. Huang
Neuron
2016
Corpus ID: 3768726
Highly Cited
2013
Highly Cited
2013
The prolyl-isomerase Pin1 activates the mitochondrial death program of p53
G. Sorrentino
,
M. Mioni
,
+5 authors
G. Del Sal
Cell Death and Differentiation
2013
Corpus ID: 14344290
In response to intense stress, the tumor protein p53 (p53) tumor suppressor rapidly mounts a direct mitochondrial death program…
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Highly Cited
2011
Highly Cited
2011
Phosphorylation of TCF Proteins by Homeodomain-interacting Protein Kinase 2*
H. Hikasa
,
S. Sokol
The Journal of Biological Chemistry
2011
Corpus ID: 26003276
Wnt pathways play essential roles in cell proliferation, morphogenesis, and cell fate specification during embryonic development…
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Review
2010
Review
2010
Unfolded p53 in the pathogenesis of Alzheimer's disease: is HIPK2 the link?
S. Stanga
,
C. Lanni
,
S. Govoni
,
D. Uberti
,
G. D’Orazi
,
M. Racchi
Aging
2010
Corpus ID: 10080971
p53 transcriptional activity depends mainly on posttranslational modifications and protein/protein interaction. Another important…
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Highly Cited
2006
Highly Cited
2006
Phosphorylation-dependent control of Pc2 SUMO E3 ligase activity by its substrate protein HIPK2.
A. Roscic
,
A. Möller
,
+5 authors
M. Schmitz
Molecular cell
2006
Corpus ID: 21828844
2006
2006
Transcriptional Activation of the SALL1 by the Human SIX1 Homeodomain during Kidney Development*
L. Chai
,
Jianchang Yang
,
+4 authors
Yupo Ma
Journal of Biological Chemistry
2006
Corpus ID: 9926231
SALL1 is a member of the SAL gene family that encodes a group of putative developmental transcription factors. SALL1 plays a…
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2005
2005
Covalent modification of human homeodomain interacting protein kinase 2 by SUMO-1 at lysine 25 affects its stability.
E. Gresko
,
A. Möller
,
A. Roscic
,
M. Schmitz
Biochemical and biophysical research…
2005
Corpus ID: 37497509
2005
2005
Desumoylation of homeodomain‐interacting protein kinase 2 (HIPK2) through the cytoplasmic‐nuclear shuttling of the SUMO‐specific protease SENP1
Y. Kim
,
Ki Sa Sung
,
Sook-Jeong Lee
,
Yong-Ou Kim
,
C. Choi
,
Yongsok Kim
FEBS letters
2005
Corpus ID: 13388952
2002
2002
HIPK2 associates with RanBPM.
Ying Wang
,
E. Marion Schneider
,
Xin Li
,
Irina Duttenhöfer
,
K. Debatin
,
H. Hug
Biochemical and biophysical research…
2002
Corpus ID: 22900925
Highly Cited
1999
Highly Cited
1999
Covalent modification of the homeodomain-interacting protein kinase 2 (HIPK2) by the ubiquitin-like protein SUMO-1.
Y. H. Kim
,
C. Y. Choi
,
Y. Kim
Proceedings of the National Academy of Sciences…
1999
Corpus ID: 36198199
Posttranslational modifications such as ubiquitination and phosphorylation play an important role in the regulation of cellular…
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