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HIPK2 protein, human

Known as: homeodomain interacting protein kinase 2, human, Homeodomain-Interacting Protein Kinase 2, Homeodomain Interacting Protein Kinase 2 
Homeodomain-interacting protein kinase 2 (1198 aa, ~131 kDa) is encoded by the human HIPK2 gene. This protein plays a role in protein phosphorylation… Expand
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Persistent accumulation of misfolded proteins causes endoplasmic reticulum (ER) stress, a prominent feature in many… Expand
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Highly Cited
2013
Highly Cited
2013
In response to intense stress, the tumor protein p53 (p53) tumor suppressor rapidly mounts a direct mitochondrial death program… Expand
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Highly Cited
2011
Highly Cited
2011
Wnt pathways play essential roles in cell proliferation, morphogenesis, and cell fate specification during embryonic development… Expand
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Review
2010
Review
2010
p53 transcriptional activity depends mainly on posttranslational modifications and protein/protein interaction. Another important… Expand
Highly Cited
2006
Highly Cited
2006
Sumoylation serves to control key cellular functions, but the regulation of SUMO E3 ligase activity is largely unknown. Here we… Expand
2006
2006
SALL1 is a member of the SAL gene family that encodes a group of putative developmental transcription factors. SALL1 plays a… Expand
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2005
2005
The modification of homeodomain‐interacting protein kinase 2 (HIPK2) by small ubiquitin‐like modifier 1 (SUMO‐1) plays an… Expand
2005
2005
The HIPK2 protein is a critical regulator of apoptosis and functionally interacts with p53 to increase gene expression. Here we… Expand
2002
2002
Using the yeast two-hybrid system, we have identified the Ran-binding protein (RanBPM) as an interaction partner of homeodomain… Expand
Highly Cited
1999
Highly Cited
1999
  • Y. Kim, C. Choi, Y. Kim
  • Proceedings of the National Academy of Sciences…
  • 1999
  • Corpus ID: 36198199
Posttranslational modifications such as ubiquitination and phosphorylation play an important role in the regulation of cellular… Expand