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HIPK2 protein, human

Known as: homeodomain interacting protein kinase 2, human, Homeodomain-Interacting Protein Kinase 2, Homeodomain Interacting Protein Kinase 2 
Homeodomain-interacting protein kinase 2 (1198 aa, ~131 kDa) is encoded by the human HIPK2 gene. This protein plays a role in protein phosphorylation… 
National Institutes of Health

Related topics

Related topics

13 relations

Broader (2)

Carrier ProteinsProtein-Serine-Threonine Kinases
Cell Cycle ControlCell NucleusEnzyme GeneHIPK2 gene
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Papers overview

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Highly Cited
2016
Highly Cited
2016
Activation of HIPK2 Promotes ER Stress-Mediated Neurodegeneration in Amyotrophic Lateral Sclerosis
Highly Cited
2013
Highly Cited
2013
The prolyl-isomerase Pin1 activates the mitochondrial death program of p53
In response to intense stress, the tumor protein p53 (p53) tumor suppressor rapidly mounts a direct mitochondrial death program… 
Highly Cited
2011
Highly Cited
2011
Phosphorylation of TCF Proteins by Homeodomain-interacting Protein Kinase 2*
Wnt pathways play essential roles in cell proliferation, morphogenesis, and cell fate specification during embryonic development… 
Review
2010
Review
2010
Unfolded p53 in the pathogenesis of Alzheimer's disease: is HIPK2 the link?
p53 transcriptional activity depends mainly on posttranslational modifications and protein/protein interaction. Another important… 
Highly Cited
2006
Highly Cited
2006
Phosphorylation-dependent control of Pc2 SUMO E3 ligase activity by its substrate protein HIPK2.
2006
2006
Transcriptional Activation of the SALL1 by the Human SIX1 Homeodomain during Kidney Development*
SALL1 is a member of the SAL gene family that encodes a group of putative developmental transcription factors. SALL1 plays a… 
2005
2005
Covalent modification of human homeodomain interacting protein kinase 2 by SUMO-1 at lysine 25 affects its stability.
2005
2005
Desumoylation of homeodomain‐interacting protein kinase 2 (HIPK2) through the cytoplasmic‐nuclear shuttling of the SUMO‐specific protease SENP1
2002
2002
HIPK2 associates with RanBPM.
Highly Cited
1999
Highly Cited
1999
Covalent modification of the homeodomain-interacting protein kinase 2 (HIPK2) by the ubiquitin-like protein SUMO-1.
Posttranslational modifications such as ubiquitination and phosphorylation play an important role in the regulation of cellular… 
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