HHV8 ORF59 Gene

Known as: Human Herpesvirus-8 ORF59 Gene, ORF59, Human Herpesvirus-8 Open Reading Frame 59 Gene 
HHV8 ORF59, which encodes DNA polymerase processivity factor protein, plays a role in viral DNA replication.
National Institutes of Health

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Lytic PhaseORF59 protein, Human herpesvirus 8Transcriptional ActivationVirus Physiological Phenomena
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Papers overview

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2008
2008
Herpes zoster with skin lesions and meningitis caused by 2 different genotypes of the Oka varicella-zoster virus vaccine.
A previously healthy boy who had received varicella vaccine developed herpes zoster with meningitis. The vaccine strain recovered… (More)
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Highly Cited
2007
Highly Cited
2007
In vivo-restricted and reversible malignancy induced by human herpesvirus-8 KSHV: a cell and animal model of virally induced Kaposi's sarcoma.
Transfection of a Kaposi's sarcoma (KS) herpesvirus (KSHV) Bacterial Artificial Chromosome (KSHVBac36) into mouse bone marrow… (More)
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2007
2007
Targeted disruption of Kaposi's sarcoma-associated herpesvirus ORF57 in the viral genome is detrimental for the expression of ORF59, K8alpha, and K8.1 and the production of infectious virus.
Kaposi's sarcoma-associated herpesvirus (KSHV) ORF57 regulates viral gene expression at the posttranscriptional level during… (More)
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2006
2006
Gene structure and expression of Kaposi's sarcoma-associated herpesvirus ORF56, ORF57, ORF58, and ORF59.
Though similar to those of herpesvirus saimiri and Epstein-Barr virus (EBV), the Kaposi's sarcoma-associated herpesvirus (KSHV… (More)
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2006
2006
Structural and functional analyses of Kaposi sarcoma-associated herpesvirus ORF57 nuclear localization signals in living cells.
Kaposi sarcoma-associated herpesvirus (KSHV) ORF57 is a multifunctional, nuclear protein involved in post-transcriptional… (More)
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Highly Cited
2005
Highly Cited
2005
A Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 ORF50 deletion mutant is defective for reactivation of latent virus and DNA replication.
Kaposi's sarcoma-associated herpesvirus (also called human herpesvirus type 8 [HHV8]) latently infects a number of cell types… (More)
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Highly Cited
2001
Highly Cited
2001
Origin-independent assembly of Kaposi's sarcoma-associated herpesvirus DNA replication compartments in transient cotransfection assays and association with the ORF-K8 protein and cellular PML.
Six predicted Kaposi's sarcoma virus herpesvirus (KSHV) proteins have homology with other well-characterized herpesvirus core DNA… (More)
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Highly Cited
2000
Highly Cited
2000
Expression and localization of human herpesvirus 8-encoded proteins in primary effusion lymphoma, Kaposi's sarcoma, and multicentric Castleman's disease.
To investigate the expression of human herpesvirus 8 (HHV8)-encoded proteins in the cells of primary effusion lymphoma (PEL… (More)
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Review
1999
Review
1999
Viral infections of the gastrointestinal tract.
Acute gastroenteritis is common in adults. It can occur in institutional epidemics or epidemics of food-borne illness; in these… (More)
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1999
1999
Expression and antigenicity of human herpesvirus 8 encoded ORF59 protein in AIDS-associated Kaposi's sarcoma.
Human herpesvirus 8 (HHV-8, Kaposi's sarcoma-associated herpesvirus, KSHV) is a new herpes virus isolated from patients with AIDS… (More)
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