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HHV8 ORF59 Gene

Known as: Human Herpesvirus-8 ORF59 Gene, ORF59, Human Herpesvirus-8 Open Reading Frame 59 Gene 
HHV8 ORF59, which encodes DNA polymerase processivity factor protein, plays a role in viral DNA replication.
National Institutes of Health

Related topics

Related topics

5 relations
Lytic PhaseORF59 protein, Human herpesvirus 8Transcriptional ActivationVirus Physiological Phenomena

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Kaposi's Sarcoma-Associated Herpesvirus ORF57 Interacts with Cellular RNA Export Cofactors RBM15 and OTT3 To Promote Expression of Viral ORF59
ABSTRACT Kaposi's sarcoma-associated herpesvirus (KSHV) encodes ORF57, which promotes the accumulation of specific KSHV mRNA… 
Highly Cited
2009
Highly Cited
2009
Genome-wide identification of binding sites for Kaposi's sarcoma-associated herpesvirus lytic switch protein, RTA.
Highly Cited
2008
Highly Cited
2008
Genetic disruption of KSHV major latent nuclear antigen LANA enhances viral lytic transcriptional program.
Highly Cited
2007
Highly Cited
2007
In vivo-restricted and reversible malignancy induced by human herpesvirus-8 KSHV: a cell and animal model of virally induced Kaposi's sarcoma.
Highly Cited
2006
Highly Cited
2006
Structural and Functional Analyses of Kaposi Sarcoma-associated Herpesvirus ORF57 Nuclear Localization Signals in Living Cells*
Kaposi sarcoma-associated herpesvirus (KSHV) ORF57 is a multifunctional, nuclear protein involved in post-transcriptional… 
Highly Cited
2004
Highly Cited
2004
Amplification of the Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 lytic origin of DNA replication is dependent upon a cis-acting AT-rich region and an ORF50 response element and the…
Highly Cited
2001
Highly Cited
2001
Origin-Independent Assembly of Kaposi's Sarcoma-Associated Herpesvirus DNA Replication Compartments in Transient Cotransfection Assays and Association with the ORF-K8 Protein and Cellular PML
ABSTRACT Six predicted Kaposi's sarcoma virus herpesvirus (KSHV) proteins have homology with other well-characterized herpesvirus… 
Highly Cited
2001
Highly Cited
2001
HHV‐8 infection status of AIDS‐unrelated and AIDS‐associated multicentric Castleman's disease
Multicentric Castleman's disease (MCD) is a clinicopathologically defined entity characterized by systemic lymphadenopathy with… 
Highly Cited
2001
Highly Cited
2001
Major histocompatibility complex class I molecules are down-regulated at the cell surface by the K5 protein encoded by Kaposi's sarcoma-associated herpesvirus/human herpesvirus-8.
The expression of major histocompatibility complex class I (MHC-I) molecules at the cell surface was down-regulated in BC-3 cells… 
Highly Cited
2000
Highly Cited
2000
Expression and localization of human herpesvirus 8-encoded proteins in primary effusion lymphoma, Kaposi's sarcoma, and multicentric Castleman's disease.
To investigate the expression of human herpesvirus 8 (HHV8)-encoded proteins in the cells of primary effusion lymphoma (PEL… 
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