HFE protein, human

Known as: HJV protein, human, MHC Class I-Like Protein HFE, HLA H antigen, human 
Hereditary hemochromatosis protein (348 aa, ~40 kDa) is encoded by the human HFE gene. This protein plays a role in the regulation of transport of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1999-2018
012319992018

Papers overview

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2013
2013
Hepcidin is a key hormone that is involved in the control of iron homeostasis in the body. Physiologically, hepcidin is… (More)
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2011
2011
The hereditary hemochromatosis protein HFE promotes the expression of hepcidin, a circulating hormone produced by the liver that… (More)
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2010
2010
Hereditary hemochromatosis is caused by mutations in the hereditary hemochromatosis protein (HFE), transferrin-receptor 2 (TfR2… (More)
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Highly Cited
2009
Highly Cited
2009
The mechanisms that allow the body to sense iron levels in order to maintain iron homeostasis are unknown. Patients with the most… (More)
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2008
2008
Lack of functional hereditary hemochromatosis protein, HFE, causes iron overload predominantly in hepatocytes, the major site of… (More)
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Highly Cited
2006
Highly Cited
2006
HFE and transferrin receptor 2 (TFR2) are membrane proteins integral to mammalian iron homeostasis and associated with human… (More)
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2003
2003
The mechanisms by which the hereditary hemochromatosis protein, HFE, decreases transferrin-mediated iron uptake were examined… (More)
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2000
2000
The transferrin receptor (TfR) interacts with two proteins important for iron metabolism, transferrin (Tf) and HFE, the protein… (More)
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Highly Cited
1999
Highly Cited
1999
HFE is the protein product of the gene mutated in the autosomal recessive disease hereditary hemochromatosis (Feder, J. N… (More)
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1999
1999
A transfectant HeLa cell clone expressing HFE under the control of a tetracycline-repressible promoter was generated. HFE… (More)
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