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HES4 gene

Known as: Hairy and Enhancer of Split 4 (Drosophila) Gene, hes family bHLH transcription factor 4, HES4 
This gene plays a role in the repression of transcription.
National Institutes of Health

Papers overview

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2015
2015
Basic helix-loop-helix (bHLH) transcription factors are pivotal regulators of cellular differentiation and development. The bHLH… Expand
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2015
2015
NOTCH regulates stem cells during normal development and stemlike cells in cancer, but the roles of NOTCH in the lethal pediatric… Expand
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Highly Cited
2014
Highly Cited
2014
UNLABELLED Next-generation sequencing was used to identify Notch mutations in a large collection of diverse solid tumors. NOTCH1… Expand
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2013
2013
The Notch pathway can have both oncogenic and tumor suppressor roles, depending on cell context. For example, Notch signaling… Expand
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2012
2012
The retina of fish and amphibian contains genuine neural stem cells located at the most peripheral edge of the ciliary marginal… Expand
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2012
2012
Purpose: We aimed to assess the biologic activity of PF-03084014 in breast xenograft models. The biomarkers for mechanism and… Expand
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2010
2010
Basic helix-loop-helix (bHLH) transcription factors are essential for lymphocytic differentiation. Here, we have analyzed the… Expand
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Highly Cited
2007
Highly Cited
2007
Notch signaling pathway maintains stem cells through transcriptional activation of HES/HEY family members to repress tissue… Expand
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2006
2006
The 5T4 oncofoetal antigen is a cell surface glycoprotein that is transiently expressed during mouse ES cell differentiation and… Expand
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Highly Cited
2004
Highly Cited
2004
Human embryonic stem (ES) cell lines that have the ability to self-renew and differentiate into specific cell types have been… Expand
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