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HES4 gene

Known as: Hairy and Enhancer of Split 4 (Drosophila) Gene, hes family bHLH transcription factor 4, HES4 
This gene plays a role in the repression of transcription.
National Institutes of Health

Papers overview

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2017
2017
Introduction Notch signalling, an evolutionarily conserved mechanism of cellular differentiation and tissue remodelling, is… 
Highly Cited
2015
Highly Cited
2015
Abstract NOTCH regulates stem cells during normal development and stemlike cells in cancer, but the roles of NOTCH in the lethal… 
Highly Cited
2014
Highly Cited
2014
UNLABELLED Next-generation sequencing was used to identify Notch mutations in a large collection of diverse solid tumors. NOTCH1… 
Highly Cited
2012
Highly Cited
2012
Purpose: We aimed to assess the biologic activity of PF-03084014 in breast xenograft models. The biomarkers for mechanism and… 
2012
2012
The retina of fish and amphibian contains genuine neural stem cells located at the most peripheral edge of the ciliary marginal… 
Highly Cited
2007
Highly Cited
2007
Notch signaling pathway maintains stem cells through transcriptional activation of HES/HEY family members to repress tissue… 
Highly Cited
2004
Highly Cited
2004
Human embryonic stem (ES) cell lines that have the ability to self‐renew and differentiate into specific cell types have been… 
2004
2004
Activation of Notch signaling pathway leads to nuclear translocation of Notch intracellular domain (NIC), and transcriptional…