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HERC5 gene

Known as: HECT DOMAIN AND RCC1-LIKE DOMAIN 5, CYCLIN E-BINDING PROTEIN 1, HERC5 
This gene plays a role in the regulation of the cell cycle by mediating cyclin interactions.
National Institutes of Health

Papers overview

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2012
2012
Genomes contain tandem repeats that are at risk of internal rearrangements and a threat to genome integrity. Here, we… Expand
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Highly Cited
2012
Highly Cited
2012
IntroductionB cell depletion therapy is efficacious in rheumatoid arthritis (RA) patients failing on tumor necrosis factor (TNF… Expand
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Highly Cited
2010
Highly Cited
2010
Virus infection induces host antiviral responses, including induction of type I interferons. Transcription factor interferon… Expand
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Highly Cited
2010
Highly Cited
2010
Ubiquitin-like protein ISG15, which is robustly induced by IFN or virus, is implicated to inhibit influenza A virus (IAV) in vivo… Expand
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Highly Cited
2009
Highly Cited
2009
In budding yeast, the Pif1 DNA helicase is involved in the maintenance of both nuclear and mitochondrial genomes, but its role in… Expand
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Highly Cited
2006
Highly Cited
2006
ISG15 is an interferon (IFN)-alpha/beta-induced ubiquitin-like protein that is conjugated to cellular proteins during innate… Expand
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Highly Cited
2006
Highly Cited
2006
Type I IFNs induce the expression of IFN-stimulated gene 15 (ISG15) and its conjugation to cellular targets. ISGylation is a… Expand
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2006
2006
Genomes contain tandem repeat blocks that are at risk of expansion or contraction. The mechanisms of destabilization of the human… Expand
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2002
2002
One of the most frequent deletions in hepatocellular carcinoma (HCC) is that involving the long arm of chromosome 4 (30 to 70% of… Expand
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Highly Cited
1994
Highly Cited
1994
Some minisatellite structures are the site of high rates of DNA recombination in non-pathological situations, with an excess of… Expand
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