FAQ

HEMGN wt Allele

Known as: EDAG, EDAG-1, Hemogen wt Allele 
Human HEMGN wild-type allele is located in the vicinity of 9q22.33 and is approximately 18 kb in length. This allele, which encodes hemogen protein… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2001-2018
01220012018

Related topics

Related topics

4 relations
Cell Differentiation processHematopoiesisHemogen

Broader (1)

HEMGN gene

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
HEMGN wt Allele
Cell Differentiation process
Hematopoiesis
HEMGN gene
Hemogen

Papers overview

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2014
2014
EDAG positively regulates erythroid differentiation and modifies GATA1 acetylation through recruiting p300.
Erythroid differentiation-associated gene (EDAG) has been considered to be a transcriptional regulator that controls… (More)
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2012
2012
Erythroid differentiation-associated gene interacts with NPM1 (nucleophosmin/B23) and increases its protein stability, resisting cell apoptosis.
Erythroid differentiation-associated gene (EDAG) is a haematopoietic tissue-specific transcription regulator that plays a key… (More)
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2010
2010
Over-expression of EDAG in the myeloid cell line 32D: induction of GATA-1 expression and erythroid/megakaryocytic phenotype.
Erythroid differentiation-associated gene (EDAG), a hematopoietic tissue-specific transcription regulator, plays a key role in… (More)
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2008
2008
Suppression of EDAG gene expression by phorbol 12-myristate 13-acetate is mediated through down-regulation of GATA-1.
EDAG, a hematopoietic tissue-specific protein, is involved in the regulation of proliferation, differentiation and apoptosis of… (More)
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2007
2007
Overexpression of a hematopoietic transcriptional regulator EDAG induces myelopoiesis and suppresses lymphopoiesis in transgenic mice
Erythroid differentiation-associated gene (EDAG) is a hematopoietic tissue-specific gene that is highly expressed in the earliest… (More)
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2007
2007
Down-regulation of EDAG expression by retrovirus-mediated small interfering RNA inhibits the growth and IL-8 production of leukemia cells.
Embryonic development associated gene (EDAG), which is overexpressed in hematopoietic neoplasms and leukemia cell lines, has been… (More)
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2006
2006
The GATA site-dependent hemogen promoter is transcriptionally regulated by GATA1 in hematopoietic and leukemia cells
Hemgn (a gene symbol for hemogen in mouse, EDAG in human and RP59 in rat) encodes a nuclear protein that is highly expressed in… (More)
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2004
2004
EDAG regulates the proliferation and differentiation of hematopoietic cells and resists cell apoptosis through the activation of nuclear factor-κB
AbstractErythroid differentiation-associated gene (EDAG) is considered to be a human hematopoiesis-specific gene. Here, we… (More)
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2003
2003
Alternative promoters and polyadenylation regulate tissue-specific expression of Hemogen isoforms during hematopoiesis and spermatogenesis.
Hemogen is a nuclear protein encoded by HEMGN (also known as hemogen in mouse, EDAG in human and RP59 in rat). It is considered… (More)
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2001
2001
Hemogen is a novel nuclear factor specifically expressed in mouse hematopoietic development and its human homologue EDAG maps to chromosome 9q22, a region containing breakpoints of hematological…
We cloned a novel murine gene, designated Hemogen (hemopoietic gene), which was sequentially expressed in active hematopoietic… (More)
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