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HAND2 wt Allele

Known as: Hed, Thing2, Heart and Neural Crest Derivatives Expressed 2 wt Allele 
Human HAND2 wild-type allele is located in the vicinity of 4q33 and is approximately 5 kb in length. This allele, which encodes heart- and neural… 
National Institutes of Health

Related topics

Related topics

7 relations

Broader (1)

HAND2 gene
Heart- and Neural Crest Derivatives-Expressed Protein 2Homo sapiensNFAT PathwayOrganogenesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Transcriptional changes in chick wing bud polarization induced by retinoic acid
Background: Retinoic acid is implicated in the induction of the gene encoding Sonic hedgehog (Shh) that specifies anteroposterior… 
2005
2005
Restricted response of mesencephalic neural crest to sympathetic differentiation signals in the trunk.
2004
2004
Differential cooperation between dHAND and three different E-proteins.
Highly Cited
2003
Highly Cited
2003
The Interaction between dHAND and Arix at the Dopamine β-Hydroxylase Promoter Region Is Independent of Direct dHAND Binding to DNA*
Dopamine β-hydroxylase (DBH) catalyzes the production of norepinephrine, and its expression defines the noradrenergic phenotype… 
2002
2002
Cardiac phenotypes in chromosome 4q− syndrome with and without a deletion of the dHAND gene
Purpose: Terminal deletions of chromosome 4q are commonly associated with cardiovascular malformations (CVMs). The dHAND gene… 
2002
2002
Tooth-type specific expression of dHAND/Hand2: possible involvement in murine lower incisor morphogenesis
Abstract. dHAND/Hand2 is a basic helix-loop-helix transcription factor required for the development of the heart, pharyngeal… 
2001
2001
Human eHAND, but not dHAND, is down-regulated in cardiomyopathies.
The progression of cardiomyopathy to congestive heart failure is often associated with the expression of fetal cardiac-specific… 
2000
2000
Developmental biology: Giving limbs a hand
Specification of the vertebrate limb by an embryo requires a complicated set of molecular instructions and, early on, the… 
1997
1997
Right and left go dHAND and eHAND
Review
1996
Review
1996
Vertebrate heart development.
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