Semantic Scholar uses AI to extract papers important to this topic.
MacroH2A histone variants suppress tumor progression and act as epigenetic barriers to induced pluripotency. How they impart… Expand The histone variant macroH2A occupies large repressive domains throughout the genome; however, mechanisms underlying its precise… Expand Erythropoiesis is a tightly regulated process. Development of red blood cells occurs through differentiation of hematopoietic… Expand Aims The macroH2A histone variants are epigenetic marks for inactivated chromatin. In this study, we examined the expression of… Expand Dynamic exchange of a subset of nucleosomes in vivo plays important roles in epigenetic inheritance of chromatin states… Expand The chromatin template imposes an epigenetic barrier during the process of somatic cell reprogramming. Here, using fibroblasts… Expand Lung cancer is the leading cause of cancer deaths. Despite optimal diagnosis and early treatment, many patients die of recurrent… Expand Age is the largest single risk factor for the development of cancer in mammals. Age-associated chromosomal changes, such as… Expand MacroH2A1 is an unusual variant of the core histone H2A which is enriched in chromatin on the inactive X chromosome of female… Expand MACROH2As are core histones that have a unique hybrid structure consisting of an amino-terminal domain that closely resembles a… Expand