Guanylyl Imidodiphosphate

Known as: Gpp(NH)p, Guanosine 5'-(Beta,Gamma-Imido)Triphosphate, Guanyl 5' Imidodiphosphate 
A non-hydrolyzable analog of GTP, in which the oxygen atom bridging the beta to the gamma phosphate is replaced by a nitrogen atom. It binds tightly… (More)
National Institutes of Health

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Highly Cited
2004
Highly Cited
2004
STUDY DESIGN In vitro assays were performed with bone-forming cells isolated from 41 patients with adolescent idiopathic… (More)
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Review
2001
Review
2001
Cardiovascular diseases are often accompanied and aggravated by pathologic platelet activation. Tight regulation of platelet… (More)
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Highly Cited
1994
Highly Cited
1994
Pan-kinesin peptide antibodies (Cole, D. G., Cande, W. Z., Baskin, R. J., Skoufias, D. A., Hogan, C. J., and Scholey, J. M. (1992… (More)
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Highly Cited
1993
Highly Cited
1993
The guanosine triphosphate (GTP)-binding protein Ras functions in regulating growth and differentiation; however, little is known… (More)
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Highly Cited
1993
Highly Cited
1993
Calcium influx in electrically non-excitable cells is regulated by the filling state of intracellular calcium stores. Depletion… (More)
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Highly Cited
1992
Highly Cited
1992
Two cell lines were created by transfecting cDNAs of the human D2 receptor or the recently cloned human D3 receptor to CHO cells… (More)
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Highly Cited
1992
Highly Cited
1992
In order to investigate the general cause of beta-adrenergic receptor neuroeffector abnormalities in the failing human heart, we… (More)
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Highly Cited
1990
Highly Cited
1990
In myocardial membranes from hearts with dilated cardiomyopathy (DCM), there was a 37% increase of the Gi alpha-protein as… (More)
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Highly Cited
1977
Highly Cited
1977
Treatment of turkey erthrocyte membranes with cholera toxin caused an enhancement of the basal and catecholamine-stimulated… (More)
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1974
1974
The GTP analog 5’-guanylyl-imidodiphosphate (Gpp(NH)p) caused marked stimulation of basal and catecholamine (isoproterenol… (More)
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