Growth Hormone Receptor Antagonist

Known as: GHR Antagonist, Growth Hormone Binding Protein Antagonist 
Any of the synthetic agents that bind to and antagonize growth hormone receptors, resulting in inhibition of somatotrophic actions triggered by… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

2000-2016
01220002016

Papers overview

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2015
2015
In general, traditional growth hormone receptor antagonist can be divided into two major classes: growth hormone (GH) analogues… (More)
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2011
2011
Exploration of construction, function and interaction of human growth hormone and growth hormone receptor in details resulted in… (More)
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2007
2007
Several classes of pharmacological agents are approved for the medical therapy of acromegaly, including dopamine agonists… (More)
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2005
2005
CONTEXT Pegvisomant is a GH receptor antagonist that blocks the peripheral actions of GH in acromegaly. Pegvisomant, in contrast… (More)
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Review
2004
Review
2004
At present, diabetic kidney disease affects about 15-20% of all Type 1 diabetic patients and 20-40% of all patients with Type 2… (More)
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2002
2002
Growth hormone (GH) and IGFs have a long distinguished history in diabetes, with possible participation in the development of… (More)
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2002
2002
Growth hormone hypersecretion is a known cause of insulin resistance. This change in insulin sensitivity is believed to be… (More)
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2001
2001
BACKGROUND Pegvisomant is a new growth hormone receptor antagonist that improves symptoms and normalises insulin-like growth… (More)
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2001
2001
The roles of GH and its receptor (GHR) in metabolic control are not yet fully understood. We studied the roles of GH and the GHR… (More)
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Review
2000
Review
2000
Growth hormone receptor (GHR) dimerization is a prerequisite to the generation of growth hormone (GH) action. Pegvisomant is a… (More)
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