Growth Factor Inhibition

Growth Factor Inhibition involves interference with, or restraint of, the activities of extracellular signaling molecules (ligands) involved in the… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2017
024619862017

Papers overview

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2014
2014
To inhibit vascular changes in diabetic retinopathy, inhibiting vascular endothelial growth factor (VEGF) has become a mainstay… (More)
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Highly Cited
2013
Highly Cited
2013
PURPOSE To report 36-month outcomes of RIDE (NCT00473382) and RISE (NCT00473330), trials of ranibizumab in diabetic macular edema… (More)
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Highly Cited
2012
Highly Cited
2012
PURPOSE To evaluate the efficacy and safety of intravitreal ranibizumab in diabetic macular edema (DME) patients. DESIGN Two… (More)
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2011
2011
The main factor involved in neovascularization of ectopic endometrial tissue in endometriosis is the vascular endothelial growth… (More)
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Highly Cited
2010
Highly Cited
2010
AMG 386 is an investigational first-in-class peptide-Fc fusion protein (peptibody) that inhibits angiogenesis by preventing the… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE Bevacizumab provides a survival benefit in first- and second-line metastatic colorectal cancer (mCRC). In a large… (More)
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2008
2008
Antiangiogenic therapy improves survival in patients with advanced stage cancers. Currently, there are no reliable predictors or… (More)
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2007
2007
Vascular endothelial growth factor (VEGF) receptor blockade impairs lung growth and decreases nitric oxide (NO) production in… (More)
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Highly Cited
2002
Highly Cited
2002
A mechanism that triggers neuronal apoptosis has been characterized. We report that the cell cycle-regulated protein kinase Cdc2… (More)
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Highly Cited
1999
Highly Cited
1999
Mesangial cell proliferation and matrix accumulation, driven by platelet-derived growth factor (PDGF), contribute to many… (More)
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