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Graft vs Leukemia Effect

Known as: Effects, Graft-vs-Leukemia, Response, Graft-vs-Leukemia, Graft-vs-Leukemia Responses 
an advantageous side-effect of a graft-vs-host reaction in which a leukemia patient is first irradiated to kill residual leukemic cells and is then… 
National Institutes of Health

Related topics

Related topics

4 relations
AntigensImmunityaspects of radiation effectsphysiological aspects

Papers overview

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Highly Cited
2002
Highly Cited
2002
Allogeneic hematopoietic stem cell transplantation in ovarian carcinoma: results of five patients
Allogeneic hematopoietic stem cell transplantation is often used to treat hematologic malignancies. The efficacy of this… 
Highly Cited
1999
Highly Cited
1999
Graft-vs.-host and graft-vs.-leukemia reactions after delayed infusions of donor T-subsets.
Infusions of donor leukocytes have been given to allogeneic bone marrow recipients after transplant to treat leukemia relapse… 
Highly Cited
1998
Highly Cited
1998
Differential cytotoxicity of cord blood and bone marrow-derived natural killer cells.
Allogeneic cord blood is now being widely used as a source of stem cells for hematologic reconstitution after myeloablative… 
Highly Cited
1998
Highly Cited
1998
Kinetics of the graft-versus-leukemia response after donor leukocyte infusions for relapsed chronic myeloid leukemia after allogeneic bone marrow transplantation.
Little is known about the mechanisms and the kinetics of the so-called graft-versus-leukemia (GVL) response induced by donor… 
Highly Cited
1997
Highly Cited
1997
CD28/B7 interactions are required for sustaining the graft-versus-leukemia effect of delayed post-bone marrow transplantation splenocyte infusion in murine recipients of myeloid or lymphoid leukemia…
Graft-vs-leukemia (GVL) can reduce relapse rates after bone marrow transplantation (BMT). Delayed lymphocyte infusion (DLI) post… 
Highly Cited
1997
Highly Cited
1997
In vitro generation of allospecific human CD8+ T cells of Tc1 and Tc2 phenotype.
We have previously shown that allospecific murine CD8+ T cells of the Tc1 and Tc2 phenotype could be generated in vitro, and that… 
Highly Cited
1996
Highly Cited
1996
Physical properties of composites cured with conventional light or argon laser.
PURPOSE To evaluate and compare diametral tensile strength (DTS), compressive strength (CS) and flexural strength (FS) of a… 
Highly Cited
1995
Highly Cited
1995
Use of unrelated marrow grafts compensates for reduced graft-versus-leukemia reactivity after T-cell-depleted allogeneic marrow transplantation for chronic myelogenous leukemia.
The effect of donor/recipient histocompatibility on relapse in patients receiving T-cell-depleted (TCD) grafts for chronic… 
Highly Cited
1993
Highly Cited
1993
IL-2 reduces graft-versus-host disease and preserves a graft-versus-leukemia effect by selectively inhibiting CD4+ T cell activity.
We have recently demonstrated, in a fully MHC-mismatched murine bone marrow transplantation model, that administration of a short… 
Highly Cited
1993
Highly Cited
1993
Interferon-alpha and donor buffy coat transfusions for treatment of relapsed chronic myeloid leukemia after allogeneic bone marrow transplantation.
Eight patients with chronic myeloid leukemia relapse after allogeneic BMT were treated with IFN-alpha and buffy coat transfusions… 
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