Goodpasture antigen

Known as: Tumstatin (Human Placenta Collagen Type IV alpha3 Chain NC1 Domain), Tumstatin, alpha3(IV)NC1 peptide 
Tumstatin (245 aa, ~27 kDa) is encoded by the human COL4A3 gene. This protein is involved in the modulation of angiogenesis.

Topic mentions per year

Topic mentions per year

1953-2018
05101519532017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
The autoantigen in Goodpasture disease is the noncollagenous domain of alpha3 type IV collagen [alpha3(IV)NC1]. We previously… (More)
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Disruption of the systemic angiogenesis balance to favor enhanced angiogenesis is speculated to represent a key step in the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2003
Highly Cited
2003
We demonstrate a physiological role for tumstatin, a cleavage fragment of the alpha3 chain of type IV collagen (Col IValpha3… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Tumstatin and endostatin are two inhibitors of angiogenesis derived from precursor human collagen molecules known as alpha 3… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Synthesis and sorting of lipids are essential for membrane biogenesis; however, the mechanisms underlying the transport of… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Vascular endothelial growth factor (VEGF), a major factor mediating endothelial cell survival, migration, and proliferation… (More)
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Tumstatin is a 28-kilodalton fragment of type IV collagen that displays both anti-angiogenic and proapoptotic activity. Here we… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
2000
2000
The non-collagenous C-terminal domain of the alpha(3) chain of collagen IV is the autoantigen in Goodpasture disease, an… (More)
Is this relevant?
Highly Cited
1988
Highly Cited
1988
The organizational relationship between the recently identified alpha 3 chain of basement membrane collagen (Butkowski, R.J… (More)
Is this relevant?
1984
1984
The glomerular basement membrane antigen in Goodpasture syndrome is a collagenase-resistant molecule with a monomer molecular… (More)
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 5
Is this relevant?