Glycoprotein IIb/IIIa Antagonist

A class of agents that act by selectively inhibiting glycoprotein IIb/IIIa with anticoagulant activity. Glycoprotein IIb/IIIa antagonists bind to and… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1993-2006
024619932006

Papers overview

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2004
2004
OBJECTIVE Temporary pharmacologic inhibition of platelet function during and after cardiopulmonary bypass (CPB) (platelet… (More)
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2003
2003
OBJECTIVE Activated platelets rapidly adhere to monocytes and upregulate the expression of tissue factor (TF), the major trigger… (More)
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2003
2003
Despite major improvements in tools and significant refinements of techniques, microsurgical anastomosis still carries a… (More)
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2002
2002
The pharmacological properties of YM-57029 [4-[4-(4-carbamimidoylphenyl)-3-oxopiperazin-1-yl]piperidino]acetic acid… (More)
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2000
2000
BACKGROUND This study evaluated the effect of heparin on the platelet reactivity and the pharmacodynamic profile of abciximab… (More)
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1998
1998
BACKGROUND Inhibitors of the platelet glycoprotein IIb/IIIa receptor given intravenously have been shown to be effective in… (More)
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1997
1997
BACKGROUND Clinical trials have demonstrated that platelet glycoprotein (GP) IIb/IIIa antagonists effectively prevent acute… (More)
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1997
1997
Experimental data suggest that formation of thromboxane A2 may be suppressed during administration of a glycoprotein IIb/IIIa… (More)
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1997
1997
Platelet aggregation and thrombosis play an important role in the onset of acute coronary events. Regardless of the stimulus for… (More)
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1993
1993
BACKGROUND Fibrinogen-dependent cross-linking of glycoprotein (GP) IIb/IIIa on activated platelets is the final mechanism leading… (More)
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