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Glial Cell Line-Derived Neurotrophic Factor

Known as: GDNF Growth Factor, Glial Cell Line Derived Neurotrophic Factor, Glial Cell-Line Derived Neurotrophic Factor 
The founding member of the glial cell line-derived neurotrophic factor family. It was originally characterized as a NERVE GROWTH FACTOR promoting the… 
National Institutes of Health

Related topics

Related topics

12 relations
GDNF geneIn BloodProcess of secretionagonists

Narrower (2)

GDNF protein, humanRecombinant Glial Cell-Line Derived Neurotrophic Factor

Broader (1)

Glial Cell Line-Derived Neurotrophic Factors

Papers overview

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Highly Cited
2003
Highly Cited
2003
The Neural Cell Adhesion Molecule NCAM Is an Alternative Signaling Receptor for GDNF Family Ligands
Highly Cited
2001
Highly Cited
2001
Glial cell line derived neurotrophic factor delays photoreceptor degeneration in a transgenic rat model of retinitis pigmentosa.
We designed experiments to evaluate the therapeutic potential of glial cell line derived neurotrophic factor (GDNF) to rescue… 
Highly Cited
1999
Highly Cited
1999
Prior Exposure to Neurotrophins Blocks Inhibition of Axonal Regeneration by MAG and Myelin via a cAMP-Dependent Mechanism
Highly Cited
1998
Highly Cited
1998
Behavioral and Cellular Protection of Rat Dopaminergic Neurons by an Adenoviral Vector Encoding Glial Cell Line-Derived Neurotrophic Factor
Previously, we observed that an adenoviral (Ad) vector encoding human glial cell line-derived neurotrophic factor (GDNF… 
Highly Cited
1997
Highly Cited
1997
Intrastriatal injection of an adenoviral vector expressing glial-cell-line-derived neurotrophic factor prevents dopaminergic neuron degeneration and behavioral impairment in a rat model of Parkinson…
Glial-cell-line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor for adult nigral dopamine neurons in vivo… 
Highly Cited
1997
Highly Cited
1997
Midbrain injection of recombinant adeno-associated virus encoding rat glial cell line-derived neurotrophic factor protects nigral neurons in a progressive 6-hydroxydopamine-induced degeneration model…
A recombinant adeno-associated virus (rAAV) vector capable of infecting cells and expressing rat glial cell line-derived… 
Highly Cited
1997
Highly Cited
1997
Glial cell line-derived neurotrophic factor (GDNF) is a neurotrophic factor for sensory neurons: comparison with the effects of the neurotrophins.
We compared the effects of glial cell line-derived neurotrophic factor (GDNF) on dorsal root ganglion (DRG) sensory neurons to… 
Highly Cited
1996
Highly Cited
1996
Germline mutations in glial cell line-derived neurotrophic factor (GDNF) and RET in a Hirschsprung disease patient
Hirschsprung disease (HSCR), or congenital aganglionic megacolon, is the most common cause of congenital bowel obstruction with… 
Highly Cited
1995
Highly Cited
1995
Glial cell line-derived neurotrophic factor but not transforming growth factor beta 3 prevents delayed degeneration of nigral dopaminergic neurons following striatal 6-hydroxydopamine lesion.
Glial cell line-derived neurotrophic factor (GDNF) and transforming growth factor beta 3 (TGF-beta 3) are members of the TGF-beta… 
Highly Cited
1995
Highly Cited
1995
In vivo neurotrophic effects of GDNF on neonatal and adult facial motor neurons
MOTOR neurons require neurotrophic factor(s) for their survival during development and for maintenance of function in adulthood1… 
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