Gene Transduction Agent

Known as: Gene Therapy Vectors, Gene Transduction Vectors 
Agents used to transport genes or genetic material to a target tissue, including viruses, liposomal encapsulation, direct naked DNA injection, or… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2018
051019942018

Papers overview

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2012
2012
Protection against epigenetic silencing is a desirable feature of future gene therapy vectors, in particular for those… (More)
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2011
2011
Adeno-associated viruses (AAVs) are nonpathogenic, nonenveloped, single-stranded DNA viruses in development as gene therapy… (More)
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2009
2009
Several events of insertional mutagenesis in pre-clinical and clinical gene therapy studies have created intense interest in… (More)
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Highly Cited
2003
Highly Cited
2003
Characterizing the molecular diversity of the cell surface is critical for targeting gene therapy. Cell type–specific binding… (More)
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Highly Cited
2003
Highly Cited
2003
The presence of various levels of anti-adenovirus serotype 5 (Ad5)-neutralizing antibodies in humans is thought to contribute to… (More)
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2003
2003
Varicella-zoster virus (VZV) glycoprotein I is dispensable in cell culture but necessary for infection of human skin and T cells… (More)
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Highly Cited
2001
Highly Cited
2001
Recombinant adeno-associated viruses (AAV) are promising gene therapy vectors. Whereas AAV serotype 2-mediated gene transfer to… (More)
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2001
2001
Muscle tissue from Duchenne muscular dystrophy patients and the Dmd(mdx/mdx) (hereafter referred to as mdx) mouse is… (More)
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1999
1999
Recently, gene therapy vectors based upon the human immunodeficiency virus type 1 (HIV-1) genome have been developed. Here, we… (More)
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Highly Cited
1996
Highly Cited
1996
Ideal gene therapy vectors would be delivered intravenously to transfect only specific cells. Existing vectors only transfect… (More)
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