Gene Duplication Abnormality

Known as: Duplication, Gene Duplication 
Generation of an extra copy of a particular gene in the genome. A gene duplication abnormality may occur by gene amplification, random breakage and… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Polyploidy, or the duplication of entire genomes, has been observed in prokaryotic and eukaryotic organisms, and in somatic and… (More)
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Highly Cited
2016
Highly Cited
2016
We present the latest version of the Molecular Evolutionary Genetics Analysis (Mega) software, which contains many sophisticated… (More)
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Highly Cited
2005
Highly Cited
2005
Segmental duplications in the human genome are selectively enriched for genes involved in immunity, although the phenotypic… (More)
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Highly Cited
2004
Highly Cited
2004
How tissues generate and maintain the correct number of cells is a fundamental problem in biology. In principle, tissue turnover… (More)
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Highly Cited
2000
Highly Cited
2000
Gene duplication has generally been viewed as a necessary source of material for the origin of evolutionary novelties, but it is… (More)
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Review
1999
Review
1999
The origin of organismal complexity is generally thought to be tightly coupled to the evolution of new gene functions arising… (More)
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Highly Cited
1999
Highly Cited
1999
A tandem repeat in DNA is two or more contiguous, approximate copies of a pattern of nucleotides. Tandem repeats have been shown… (More)
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Highly Cited
1996
Highly Cited
1996
We analyzed mRNA expression of the flt3 gene in 30 patients with acute myeloid leukemia (AML) and 50 with acute lymphoblastic… (More)
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Highly Cited
1995
Highly Cited
1995
Spinal muscular atrophy (SMA) is a common fatal autosomal recessive disorder characterized by degeneration of lower motor neurons… (More)
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Highly Cited
1987
Highly Cited
1987
A variant of the cauliflower mosaic virus 35S promoter with transcriptional activity approximately tenfold higher than that of… (More)
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