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Gamma-Aminobutyric Acid Type B Receptor Subunit 2

Known as: G-Protein Coupled Receptor 51, GABA-B Receptor 2, Gb2 
Gamma-aminobutyric acid type B receptor subunit 2 (941 aa, ~106 kDa) is encoded by the human GABBR2 gene. This protein plays a role in the mediation… Expand
National Institutes of Health

Related topics

Related topics

14 relations
BrainG Protein-Coupled Receptor GenesG Protein-Coupled Receptor SignalingGABBR2 gene
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Papers overview

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Highly Cited
2008
Highly Cited
2008
Expression of GABAB Receptors Is Altered in Brains of Subjects with Autism
Autism is a neurodevelopmental disorder that is often comorbid with seizures. Gamma-aminobutyric acid (GABA) is the main… Expand
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Highly Cited
2004
Highly Cited
2004
θ Defensins Protect Cells from Infection by Herpes Simplex Virus by Inhibiting Viral Adhesion and Entry
ABSTRACT We tested the ability of 20 synthetic θ defensins to protect cells from infection by type 1 and type 2 herpes simplex… Expand
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Highly Cited
2004
Highly Cited
2004
Mixed cytomegalovirus glycoprotein B genotypes in immunocompromised patients.
On the basis of sequence variation in the UL55 gene that encodes glycoprotein B (gB), human cytomegalovirus (CMV) can be… Expand
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Highly Cited
2002
Highly Cited
2002
No Ligand Binding in the GB2 Subunit of the GABABReceptor Is Required for Activation and Allosteric Interaction between the Subunits
The GABAB receptor plays important roles in the tuning of many synapses. Although pharmacological differences have been observed… Expand
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Highly Cited
2001
Highly Cited
2001
Allosteric interactions between GB1 and GB2 subunits are required for optimal GABAB receptor function
Recent studies on G‐protein‐coupled receptors revealed that they can dimerize. However, the role of each subunit in the… Expand
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Highly Cited
2001
Highly Cited
2001
Ligand-induced signal transduction within heterodimeric GABAB receptor
γ-aminobutyric acid type B (GABAB) receptors, G protein-coupled receptors (GPCRs) for GABA, are obligate heterodimers of two… Expand
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Highly Cited
1999
Highly Cited
1999
Identification of a GABAB Receptor Subunit, gb2, Required for Functional GABAB Receptor Activity*
G protein-coupled receptors are commonly thought to bind their cognate ligands and elicit functional responses primarily as… Expand
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Highly Cited
1999
Highly Cited
1999
Activation of a Frizzled-2/β-adrenergic receptor chimera promotes Wnt signaling and differentiation of mouse F9 teratocarcinoma cells via Gαo and Gαt
The frizzled gene family of putative Wnt receptors encodes proteins that have a seven-transmembrane-spanning motif characteristic… Expand
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Highly Cited
1998
Highly Cited
1998
GABAB-receptor subtypes assemble into functional heteromeric complexes
B-type receptors for the neurotransmitter GABA (γ-aminobutyric acid) inhibit neuronal activity through G-protein-coupled second… Expand
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Highly Cited
1990
Highly Cited
1990
Comparison of the glycolipid receptor specificities of Shiga-like toxin type II and Shiga-like toxin type II variants.
The antigenically distinct Shiga-like toxins (SLTs) SLT-1 and SLT-II are cytotoxic for both Vero and HeLa cells and use Gal alpha… Expand
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