Gamma-Aminobutyric Acid Type B Receptor Subunit 2

Known as: G-Protein Coupled Receptor 51, GABA-B Receptor 2, Gb2 
Gamma-aminobutyric acid type B receptor subunit 2 (941 aa, ~106 kDa) is encoded by the human GABBR2 gene. This protein plays a role in the mediation… (More)
National Institutes of Health

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14 relations
BrainG Protein-Coupled Receptor GenesG Protein-Coupled Receptor SignalingGABBR2 gene
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Papers overview

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2009
2009
Impact of genetic polymorphisms in cytomegalovirus glycoprotein B on outcomes in solid-organ transplant recipients with cytomegalovirus disease.
BACKGROUND It is unknown whether specific viral polymorphisms affect in vivo therapeutic response in patients with… (More)
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Highly Cited
2008
Highly Cited
2008
Expression of GABAB Receptors Is Altered in Brains of Subjects with Autism
Autism is a neurodevelopmental disorder that is often comorbid with seizures. Gamma-aminobutyric acid (GABA) is the main… (More)
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2008
2008
The sialylated lipooligosaccharide outer core in Campylobacter jejuni is an important determinant for epithelial cell invasion.
Campylobacter jejuni is a frequent cause of bacterial gastroenteritis worldwide. Lipooligosaccharide (LOS) has been identified as… (More)
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2004
2004
Mixed cytomegalovirus glycoprotein B genotypes in immunocompromised patients.
On the basis of sequence variation in the UL55 gene that encodes glycoprotein B (gB), human cytomegalovirus (CMV) can be… (More)
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2004
2004
Theta defensins protect cells from infection by herpes simplex virus by inhibiting viral adhesion and entry.
We tested the ability of 20 synthetic theta defensins to protect cells from infection by type 1 and type 2 herpes simplex viruses… (More)
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Highly Cited
2001
Highly Cited
2001
Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function.
Recent studies on G-protein-coupled receptors revealed that they can dimerize. However, the role of each subunit in the… (More)
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2001
2001
The anticonvulsant, antihyperalgesic agent gabapentin is an agonist at brain gamma-aminobutyric acid type B receptors negatively coupled to voltage-dependent calcium channels.
Gabapentin (Neurontin, Pfizer Global R & D) is a novel anticonvulsant, antihyperalgesic, and antinociceptive agent with a poorly… (More)
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2000
2000
Distribution of the GABA(B) receptor subunit gb2 in rat CNS.
We have identified and isolated human and rat cDNAs for a novel receptor, gb2, with 38% homology to the GABA(B) receptors gb1a… (More)
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Highly Cited
1998
Highly Cited
1998
GABAB-receptor subtypes assemble into functional heteromeric complexes
B-type receptors for the neurotransmitter GABA (γ-aminobutyric acid) inhibit neuronal activity through G-protein-coupled second… (More)
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1985
1985
Antihepatoxic constituents of Garcinia kola seeds.
Kolaviron, a fraction of defatted methanolic extract and biflavanones of Garcinia kola seeds significantly antagonized the lethal… (More)
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