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GW1100
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National Institutes of Health
Topic mentions per year
Topic mentions per year
2006-2017
0
2
4
6
2006
2017
Related topics
Related topics
2 relations
Broader (2)
Benzoates
Pyrimidines
Related mentions per year
Related mentions per year
1936-2018
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2020
GW1100
Pyrimidines
Benzoates
Papers overview
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2017
2017
Omega-3 fatty acids regulate NLRP3 inflammasome activation and prevent behavior deficits after traumatic brain injury.
Chao Lin
,
Honglu Chao
,
+9 authors
Jing Ji
Experimental neurology
2017
Omega-3 fatty acids (ω-3 FAs) attenuate inflammation and improve neurological outcome in response to traumatic brain injury (TBI…Â
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2016
2016
Diverse effects of G-protein-coupled free fatty acid receptors on the regulation of cellular functions in lung cancer cells.
Tsubasa Kita
,
Yui Kadochi
,
+7 authors
Toshifumi Tsujiuchi
Experimental cell research
2016
Free fatty acids (FFAs) are dietary nutrients which mediate a variety of biological effects through binding to G-protein-coupled…Â
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2016
2016
Differential intracellular calcium influx, nitric oxide production, ICAM-1 and IL8 expression in primary bovine endothelial cells exposed to nonesterified fatty acids.
Anitsi Loaiza
,
MarÃa Daniella Carretta
,
Anja Taubert
,
Carlos Hermosilla
,
M. Arias - Hidalgo
,
Rafael A Burgos
BMC veterinary research
2016
BACKGROUND Nonesterified fatty acids (NEFAs) are involved in proinflammatory processes in cattle, including in the increased…Â
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2015
2015
The Anthocyanin Delphinidin 3-Rutinoside Stimulates Glucagon-Like Peptide-1 Secretion in Murine GLUTag Cell Line via the Ca2+/Calmodulin-Dependent Kinase II Pathway
Masaki Kato
,
Tsubasa Tani
,
Norihiko Terahara
,
Takanori Tsuda
PloS one
2015
Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from enteroendocrine L-cells. Although several nutrients induce…Â
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2015
2015
Opposite effects of GPR120 and GPR40 on cell motile activity induced by ethionine in liver epithelial cells.
Shuhei Ishii
,
Miku Hirane
,
Sayumi Kato
,
Nobuyuki Fukushima
,
Toshifumi Tsujiuchi
Biochemical and biophysical research…
2015
Free fatty acids (FFAs) are dietary nutrients which act as ligands for FFAs receptors. G-protein-coupled receptor 120 (GPR120…Â
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2015
2015
Tumor necrosis factor α decreases glucagon-like peptide-2 expression by up-regulating G-protein-coupled receptor 120 in Crohn disease.
Takuya Tsukahara
,
Kenji Watanabe
,
+9 authors
Tetsuo Arakawa
The American journal of pathology
2015
Glucagon-like peptide (GLP)-2, secreted by L cells in the small intestine, has anti-inflammatory effects in the gastrointestinal…Â
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2013
2013
Hypothalamic GPR40 Signaling Activated by Free Long Chain Fatty Acids Suppresses CFA-Induced Inflammatory Chronic Pain
Kazuo Nakamoto
,
Takashi Nishinaka
,
+4 authors
Shogo Tokuyama
PloS one
2013
GPR40 has been reported to be activated by long-chain fatty acids, such as docosahexaenoic acid (DHA). However, reports studying…Â
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2011
2011
Feasible Synthesis of Antagonist of GPR40 by Constructing 2-Thiouracil Ring viaAcid Mediated Cyclization.
Yongfeng Zhao
,
Yang Song
,
Xiulin Shen
,
Jiayu Liao
Heterocycles
2011
GW1100 is an antagonist of GPR40 identified by high throughput screening recently. The synthesis of GW1100 has been developed…Â
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2007
2007
Uncovering the Pharmacology of the G Protein-Coupled Receptor GPR40: High Apparent Constitutive Activity in Guanosine 5 -O-(3-[S]thio)triphosphate Binding Studies Reflects Binding of an Endogenous…
Leigh A. Stoddart
,
Andrew J. Brown
,
Graeme Milligan
2007
In cells lacking expression of Ca -mobilizing G proteins, coexpression of human GPR40 and G q allowed mediumand long-chain fatty…Â
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Highly Cited
2006
Highly Cited
2006
Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules.
Celia P Briscoe
,
Andrew J. Peat
,
+10 authors
S. Rhiannon Jenkinson
British journal of pharmacology
2006
1. Long chain fatty acids have recently been identified as agonists for the G protein-coupled receptors GPR40 and GPR120. Here…Â
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