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GW1100

 
National Institutes of Health

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2 relations

Broader (2)

BenzoatesPyrimidines

Papers overview

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2018
2018
GPR40 is a low-affinity epoxyeicosatrienoic acid receptor in vascular cells
Endothelium-derived epoxyeicosatrienoic acids (EETs) have numerous vascular activities mediated by G protein–coupled receptors… Expand
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2017
2017
Omega-3 fatty acids regulate NLRP3 inflammasome activation and prevent behavior deficits after traumatic brain injury
&NA; Omega‐3 fatty acids (&ohgr; − 3 FAs) attenuate inflammation and improve neurological outcome in response to traumatic brain… Expand
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2017
2017
Chylomicrons stimulate incretin secretion in mouse and human cells
Aims/hypothesisLipids are a potent stimulus for the secretion of glucagon-like peptide (GLP)-1 and glucose-dependent… Expand
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2015
2015
The activation of supraspinal GPR40/FFA1 receptor signalling regulates the descending pain control system
The ω‐3 polyunsaturated fatty acids exert antinociceptive effects in inflammatory and neuropathic pain; however, the underlying… Expand
2015
2015
The Anthocyanin Delphinidin 3-Rutinoside Stimulates Glucagon-Like Peptide-1 Secretion in Murine GLUTag Cell Line via the Ca2+/Calmodulin-Dependent Kinase II Pathway
Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from enteroendocrine L-cells. Although several nutrients induce… Expand
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2015
2015
Attenuation of inflammatory and neuropathic pain behaviors in mice through activation of free fatty acid receptor GPR40
BackgroundThe G-protein-coupled receptor 40 (GPR40) is suggested to function as a transmembrane receptor for medium- to long… Expand
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2015
2015
Cloning, Identification and Functional Characterization of Bovine Free Fatty Acid Receptor-1 (FFAR1/GPR40) in Neutrophils
Long chain fatty acids (LCFAs), which are ligands for the G-protein coupled receptor FFAR1 (GPR40), are increased in cow plasma… Expand
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2015
2015
Tumor necrosis factor α decreases glucagon-like peptide-2 expression by up-regulating G-protein-coupled receptor 120 in Crohn disease.
Glucagon-like peptide (GLP)-2, secreted by L cells in the small intestine, has anti-inflammatory effects in the gastrointestinal… Expand
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Highly Cited
2013
Highly Cited
2013
Hypothalamic GPR40 Signaling Activated by Free Long Chain Fatty Acids Suppresses CFA-Induced Inflammatory Chronic Pain
GPR40 has been reported to be activated by long-chain fatty acids, such as docosahexaenoic acid (DHA). However, reports studying… Expand
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Highly Cited
2006
Highly Cited
2006
Pharmacological regulation of insulin secretion in MIN6 cells through the fatty acid receptor GPR40: identification of agonist and antagonist small molecules
1 Long chain fatty acids have recently been identified as agonists for the G protein‐coupled receptors GPR40 and GPR120. Here, we… Expand
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