GW 4064

Known as: GW-4064, GW4064 
 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
UNLABELLED Mouse fibroblast growth factor 15 (FGF15) and human ortholog FGF19 have been identified as the bile acid-induced… (More)
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2008
2008
Starting from the known FXR agonist GW 4064 1a, a series of stilbene replacements were prepared. The 6-substituted 1-naphthoic… (More)
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Highly Cited
2007
Highly Cited
2007
Bile acid concentrations are controlled by a feedback regulatory pathway whereby activation of the farnesoid X receptor (FXR… (More)
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Highly Cited
2006
Highly Cited
2006
The farnesoid X receptor (FXR) is a bile acid (BA)-activated nuclear receptor that plays a major role in the regulation of BA and… (More)
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Highly Cited
2004
Highly Cited
2004
The farnesoid X receptor (FXR), an endogenous sensor for bile acids, regulates a program of genes involved in bile acid… (More)
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Highly Cited
2003
Highly Cited
2003
The human multidrug resistance gene MDR3 encodes a P-glycoprotein that belongs to the ATP-binding cassette transporter family… (More)
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Highly Cited
2003
Highly Cited
2003
Peroxisome proliferator-activated receptor alpha (PPARalpha) is a nuclear receptor that controls lipid and glucose metabolism and… (More)
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Highly Cited
2003
Highly Cited
2003
BACKGROUND & AIMS Increased serum triglyceride levels constitute a risk factor for coronary heart disease. Apolipoprotein CIII… (More)
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Highly Cited
2002
Highly Cited
2002
The multidrug resistance-associated protein 2 (MRP2, ABCC2), mediates the efflux of several conjugated compounds across the… (More)
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Highly Cited
2002
Highly Cited
2002
Serum levels of HDL are inversely correlated with the risk of coronary heart disease. The anti-atherogenic effect of HDL is… (More)
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