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GW 4064

Known as: GW-4064, GW4064 
 
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Sirtuin 1 (SIRT1) is a NAD-dependent deacetylase that is critically involved in diverse cellular processes including metabolic… Expand
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Highly Cited
2009
Highly Cited
2009
Mouse fibroblast growth factor 15 (FGF15) and human ortholog FGF19 have been identified as the bile acid–induced intestinal… Expand
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Highly Cited
2007
Highly Cited
2007
Bile acid concentrations are controlled by a feedback regulatory pathway whereby activation of the farnesoid X receptor (FXR… Expand
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Highly Cited
2006
Highly Cited
2006
Farnesoid X receptor (FXR) plays an important role in maintaining bile acid and cholesterol homeostasis. Here we demonstrate that… Expand
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Highly Cited
2006
Highly Cited
2006
The farnesoid X receptor (FXR) is a bile acid (BA)-activated nuclear receptor that plays a major role in the regulation of BA and… Expand
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Highly Cited
2003
Highly Cited
2003
Farnesoid X receptor (FXR) is a bile acid-activated transcription factor that is a member of the nuclear hormone receptor… Expand
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Highly Cited
2003
Highly Cited
2003
BACKGROUND & AIMS Increased serum triglyceride levels constitute a risk factor for coronary heart disease. Apolipoprotein CIII… Expand
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Highly Cited
2003
Highly Cited
2003
Peroxisome proliferator-activated receptor alpha (PPARalpha) is a nuclear receptor that controls lipid and glucose metabolism and… Expand
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Highly Cited
2002
Highly Cited
2002
The multidrug resistance-associated protein 2 (MRP2, ABCC2), mediates the efflux of several conjugated compounds across the… Expand
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Highly Cited
2002
Highly Cited
2002
Serum levels of HDL are inversely correlated with the risk of coronary heart disease. The anti-atherogenic effect of HDL is… Expand
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