GTF2A2 gene

The general transcription factor IID (TFIID) plays a central role in the initiation of RNA polymerase II (Pol II)-dependent… Expand

The multisubunit transcription factor IID (TFIID) is an essential component of the eukaryotic RNA polymerase II machinery that… Expand

The retinoblastoma tumor suppressor protein (pRB) is a transcriptional repressor, critical for normal cell cycle progression. We… Expand

Assembly and activity of yeast RNA polymerase II (Pol II) preinitiation complexes (PIC) was investigated with an immobilized… Expand

The oncoprotein MDM2 binds to the activation domain of the tumor suppressor p53 and inhibits its ability to stimulate… Expand

ONE of the important regulatory concepts to emerge from studies of eukaryotic gene expression is that RNA polymerase II promo… Expand

THE nuclear proto-oncoprotein Myc has been implicated in the control of cell proliferation and differentiation1–3. Myc… Expand

Two new factors required for transcription of class II genes have been identified. These factors, TFIIH and TFIIJ, were required… Expand

A family of proteins was shown to bind cooperatively with TFIID to core promoters, as previously demonstrated for the general… Expand

Transcription from the major late promoter of adenovirus type 2 DNA (including DNA sequences from 56 nucleotides upstream to 33… Expand