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GSK 2118436
Known as:
GSK-2118436A
, GSK2118436
, GSK-2118436
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National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
dabrafenib
Papers overview
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2014
2014
Title Combination Treatment for Melanoma Permalink
Stephen Mok
,
T. Graeber
,
Donald B. Kohn
,
Roger S. Lo
,
Antoni Ribas
2014
Corpus ID: 264764606
Combining immunotherapy with targeted therapy blocking oncogenic BRAF may result in improved treatments for advanced melanoma. In…
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2013
2013
Title Effect of dabrafenib on melanoma cell lines harbouring the BRAF V 600 D / R mutations Permalink
G. Gentilcore
,
G. Madonna
,
+4 authors
P. Ascierto
2013
Corpus ID: 4984431
Background: Conventional therapeutic agents are largely unsatisfactory into the treatment of malignant melanoma. Recently, an…
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2013
2013
Metabolism and Disposition of Oral Dabrafenib in Cancer Patients : Proposed Participation of Aryl Nitrogen in Carbon-Carbon Bond Cleavage via Decarboxylation following Enzymatic Oxidation s
David A. Bershas
,
D. Ouellet
,
+9 authors
L. Richards-Peterson
2013
Corpus ID: 29962144
A phase I study was conducted to assess the metabolism and excretion of [C]dabrafenib (GSK2118436; N-{3-[5-(2-amino-4-pyrimidinyl…
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