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GS-9620

National Institutes of Health

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Pteridines

Papers overview

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2018
2018
Cytokine-dependent activation of MAIT cells by the TLR8 agonist GS-9688 but not the TLR7 agonist GS-9620
2018
2018
GS‐9620 inhibits enterovirus 71 replication mainly through the NF‐&kgr;B and PI3K‐AKT signaling pathways
2018
2018
Metabolism of vesatolimod in rat, dog, and human liver microsomes: Metabolic stability assessment, metabolite identification, and interspecies comparison.
Vesatolimod (GS-9620) is an agonist of toll-like receptor (TLR7) 7, which has been developed as an anti-hepatitis B virus (HBV… 
Review
2016
Review
2016
Activating the innate immune response to counter chronic hepatitis B virus infection
ABSTRACT Introduction: Chronic infection with hepatitis B virus (HBV) is endemic to several populous parts of the world, where… 
2015
2015
From the Editor’s desk...: June 2015
2013
2013
OC-29 Antiviral activity of flavonoid-derived compounds against hepatitis B virus
2011
2011
1114 ANTI-VIRAL EFFICACY AND INDUCTION OF AN ANTIBODY RESPONSE AGAINST SURFACE ANTIGEN WITH THE TLR7 AGONIST GS-9620 IN THE WOODCHUCK MODEL OF CHRONIC HBV INFECTION
2011
2011
100 THERAPEUTIC EFFICACY OF THE TLR7 AGONIST GS-9620 FOR HBV CHRONIC INFECTION IN CHIMPANZEES
2011
2011
1129 PRECLINICAL CHARACTERIZATION OF GS-9620, A POTENT AND SELECTIVE ORAL TLR7 AGONIST
2011
2011
1130 SPREADING OF HEPATITIS B VIRUS INFECTION IN UPA MICE IS SENSED BY INNATE ANTIVIRAL DEFENSE MECHANISMS OF HUMAN HEPATOCYTES
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