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GS-9451

National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
BACKGROUND Hepatitis C virus (HCV) RNA loads serve as predictors of treatment response during interferon-based therapy. We… 
Highly Cited
2015
Highly Cited
2015
AbstractBackground As treatment for chronic hepatitis C (HCV) virus has evolved to all-oral, interferon-free directly acting… 
Highly Cited
2015
Highly Cited
2015
BACKGROUND Treatment of chronic hepatitis C virus (HCV) infection with direct-acting antivirals (DAAs) for 6 weeks achieves… 
2013
2013
ABSTRACT GS-9451 is a selective hepatitis C virus (HCV) NS3 protease inhibitor in development for the treatment of genotype 1… 
2013
2013
Background GS-9451 is a novel inhibitor of the HCV NS3/4A protease and demonstrates potent in vitro suppression of HCV genotype 1… 
2012
2012
ABSTRACT GS-9451, a novel hepatitis C virus (HCV) nonstructural 3/4a (NS3/4a) protease inhibitor, is highly active in patients… 
2012
2012
Highly Cited
2012
Highly Cited
2012
ABSTRACT The high genetic variation of hepatitis C virus (HCV) results in rapid selection of drug resistance mutations (DRMs…