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GRL 8234
Known as:
GRL-8234
, GRL8234
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Phthalic Acids
Sulfonamides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Cognitive benefits of memantine in Alzheimer's 5XFAD model mice decline during advanced disease stages
L. Devi
,
M. Ohno
Pharmacology Biochemistry and Behavior
2016
Corpus ID: 207333502
Memantine, a noncompetitive NMDA receptor antagonist with neuroprotective properties, has been used for the treatment of…
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2015
2015
Beneficial effects of the β-secretase inhibitor GRL-8234 in 5XFAD Alzheimer's transgenic mice lessen during disease progression.
L. Devi
,
Jordan J. N. Tang
,
M. Ohno
Current Alzheimer research
2015
Corpus ID: 44554670
The β-secretase enzyme BACE1, which initiates the cleavage of amyloid precursor protein (APP) into the amyloid-β (Aβ) peptide, is…
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Highly Cited
2011
Highly Cited
2011
β‐Secretase inhibitor GRL‐8234 rescues age‐related cognitive decline in APP transgenic mice
Wanpin Chang
,
Xiangping Huang
,
+5 authors
Jordan J. N. Tang
FASEB journal : official publication of the…
2011
Corpus ID: 27692770
Alzheimer disease is intimately linked to an excess amount of amyloid‐β (Aβ) in the brain. Thus, therapeutic inhibition of A…
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