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GPX5 gene

Known as: GLUTATHIONE PEROXIDASE 5, epididymal androgen-related protein, GPX5 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
A novel antioxidant formulation designed to treat male infertility associated with oxidative stress: promising preclinical evidence from animal models.
STUDY QUESTION Does a novel antioxidant formulation designed to restore redox balance within the male reproductive tract, reduce… 
2016
2016
Role of Zinc Supplementation in Testicular and Epididymal Damages in Diabetic Rat: Involvement of Nrf2, SOD1, and GPX5
Zinc (Zn) is one of the most important trace elements required for several biological processes. Diabetes negatively affects many… 
Highly Cited
2015
Highly Cited
2015
Comparative analysis of boar seminal plasma proteome from different freezability ejaculates and identification of Fibronectin 1 as sperm freezability marker
Variation in boar sperm freezability (i.e. capacity to withstand cryopreservation) between ejaculates is a limitation largely… 
Review
2015
Review
2015
ROS, thiols and thiol-regulating systems in male gametogenesis.
Highly Cited
2013
Highly Cited
2013
Epididymal specific, selenium-independent GPX5 protects cells from oxidative stress-induced lipid peroxidation and DNA mutation.
STUDY QUESTION Can selenium (Se) independent, epididymal-specific glutathione peroxidase 5 (GPX5) protect CHO-K1 cells from… 
2010
2010
Characterization of an ovary-specific glutathione peroxidase from the shrimp Metapenaeus ensis and its role in crustacean reproduction.
Highly Cited
2009
Highly Cited
2009
Epididymis seleno-independent glutathione peroxidase 5 maintains sperm DNA integrity in mice.
The mammalian epididymis provides sperm with an environment that promotes their maturation and protects them from external… 
2009
2009
Nm23‐M5 mediates round and elongated spermatid survival by regulating GPX‐5 levels
Highly Cited
2002
Highly Cited
2002
GPX5 is present in the mouse caput and cauda epididymidis lumen at three different locations
In mice, GPX5 is a secreted protein abundantly synthesized by the caput epididymidis. The protein is secreted as early as the… 
Highly Cited
1997
Highly Cited
1997
Tissue and developmental distribution, dependence upon testicular factors and attachment to spermatozoa of GPX5, a murine epididymis‐specific glutathione peroxidase
Using immunohistochemistry and Western blotting analyses, we present a detailed study of the distribution of the glutathione… 
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